December 2018

Human natural killer (NK) cell activation by luteolin from Brucea javanica leaves

There is growing interest in using natural substances from plants to potentially enhance anticancer activity. A key target in this respect is natural killer (NK) cells in order to generate an anticancer-immune response. Luteolin used in this study was derived from a local plant Brucea javanica leaves extract; through a bioassay-guided fractionation. The expression of interleukin-2 (IL-2) and interferon-γ...

Author(s): Norzila Ismail, Hasmah Abdullah, Veronique Seidel and Dino Rotondo