Journal of
Cancer Research and Experimental Oncology

  • Abbreviation: J. Cancer Res. Exp. Oncol.
  • Language: English
  • ISSN: 2141-2243
  • DOI: 10.5897/JCREO
  • Start Year: 2009
  • Published Articles: 56

Table of Content: November 2011; 3(8)

November 2011

Loss of heterozygosity (LOH) of deleted in colorectal cancer (DCC) gene and predisposition to colorectal cancer: Significant association in colorectal cancer patients of Kashmir

Loss of heterozygosity (LOH) of deleted in colorectal cancer (DCC) gene, a putative tumour suppressor gene has been implicated in development of various cancers. Here we aim to study the frequency of LOH of DCC gene in colorectal cancer (CRC) patients of Kashmir and further to assess any association with etio-pathological factors. Genomic DNA from 80 confirmed CRC tissue samples as well as adjacent normal...

Author(s): Nighat P. Khan, Arshad A. Pandith, Mahboob U. l. Hussain, Adfar Yousuf, Mosin S. Khan, Mushtaq A. Siddiqi, Khrusheed A. Wani and Syed Mudassar

November 2011

Antitumor potential of an acetogenin isolated from the seed extracts of Annona squamosa Linn.

Ethanolic herbal extract residue of the seeds of Annona squamosa Linn. were tested against Dalton’s Lymphoma Ascites (DLA) tumour cells. Then its effect on the increased lifespan of mice with DLA tumour cells was studied. At high and low dosages, it exhibited 66.67 and 56.25% increase in the lifespan. Percentage of haemoglobin (Hb) and red blood cell (RBC) counts of treated were higher than that of...

Author(s): R. M. Ganesan and K. Muthuchelian