Journal of
Diabetes and Endocrinology

  • Abbreviation: J. Diabetes Endocrinol.
  • Language: English
  • ISSN: 2141-2685
  • DOI: 10.5897/JDE
  • Start Year: 2010
  • Published Articles: 59

Full Length Research Paper

Early microalbuminuria in adolescent Type 1 diabetic patients: Experience from a pediatric endocrine clinic in a developing country

Depobam Samanta1*, V. Mallika2 and Sangeeta Yadav1
1Department of Pediatrics, Maulana Azad Medical College and Associated Lok Nayak and G.B.Pant Hospital, New Delhi, 110002, India. 2Department of Biochemistry, Maulana Azad Medical College and Associated Lok Nayak and G.B.Pant Hospital, New Delhi, 110002, India.
Email: [email protected]

  • Article Number - F9285651066
  • Vol.3(1), pp. 6-10, February 2012
  •  Accepted: 26 January 2011
  •  Published: 31 January 2012

Abstract

There are no studies of early microalbuminuria in adolescent Type 1 diabetic patients in the developing world where patients are considerably undernourished and follow conventional treatment regimens in most part. The objective was to assess the presence of microalbuminuria in Type 1 adolescent diabetes mellitus (DM) patients where patients still use conventional treatment regimen. The subjects (n = 30), in the age group of 10 to 18 years, were divided into two groups - good glycaemic (n = 16) and poor glycaemic (n = 14) control groups during end of study period based on their mean HbA1c value (<8.5 vs. ≥8.5, mean value over one year period). Though no subject with good glycaemic control developed microalbuminuria, 5 (35.7%) of the total 14 poor glycaemic control patients had microalbuminuria. Both systolic and diastolic blood pressures were higher in the microalbuminuric group. It is concluded that malnourished adolescent Type 1 diabetic patients who follow conventional treatment regimen and are poorly controlled, may develop very early microalbuminuria.

 

Key words: Diabetic nephropathy, early diagnosis, microalbuminuria.

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