Journal of
Dentistry and Oral Hygiene

  • Abbreviation: J. Dent. Oral Hyg.
  • Language: English
  • ISSN: 2141-2472
  • DOI: 10.5897/JDOH
  • Start Year: 2009
  • Published Articles: 132

Full Length Research Paper

In vitro antimicrobial activity of CatDex against Porphyromonas endodontalis

María Fernanda Mayela Carrillo-Sosa
  • María Fernanda Mayela Carrillo-Sosa
  • Universidad Autonoma de Nuevo Leon, Centro de Investigacion y Desarrollo en Ciencias de la Salud (CIDICS)/Facultad de Odontología, Calle Dr. Eduardo Aguirre Pequeño s/n, Colonia Mitras Centro, Monterrey, Nuevo Leon, 64460 Mexico.
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Idalia Rodríguez-Delgado
  • Idalia Rodríguez-Delgado
  • Universidad Autonoma de Nuevo Leon, Centro de Investigacion y Desarrollo en Ciencias de la Salud (CIDICS)/Facultad de Odontología, Calle Dr. Eduardo Aguirre Pequeño s/n, Colonia Mitras Centro, Monterrey, Nuevo Leon, 64460 Mexico.
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Jorge Jaime Flores-Trevino
  • Jorge Jaime Flores-Trevino
  • Universidad Autonoma de Nuevo Leon, Centro de Investigacion y Desarrollo en Ciencias de la Salud (CIDICS)/Facultad de Odontología, Calle Dr. Eduardo Aguirre Pequeño s/n, Colonia Mitras Centro, Monterrey, Nuevo Leon, 64460 Mexico.
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Myriam Angelica De La Garza-Ramos
  • Myriam Angelica De La Garza-Ramos
  • Universidad Autonoma de Nuevo Leon, Centro de Investigacion y Desarrollo en Ciencias de la Salud (CIDICS)/Facultad de Odontología, Calle Dr. Eduardo Aguirre Pequeño s/n, Colonia Mitras Centro, Monterrey, Nuevo Leon, 64460 Mexico.
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Elizabeth Madla-Cruz
  • Elizabeth Madla-Cruz
  • Universidad Autonoma de Nuevo Leon, Centro de Investigacion y Desarrollo en Ciencias de la Salud (CIDICS)/Facultad de Odontología, Calle Dr. Eduardo Aguirre Pequeño s/n, Colonia Mitras Centro, Monterrey, Nuevo Leon, 64460 Mexico.
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Erandi Escamilla-García
  • Erandi Escamilla-García
  • Universidad Autonoma de Nuevo Leon, Centro de Investigacion y Desarrollo en Ciencias de la Salud (CIDICS)/Facultad de Odontología, Calle Dr. Eduardo Aguirre Pequeño s/n, Colonia Mitras Centro, Monterrey, Nuevo Leon, 64460 Mexico.
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Eloy Cardenas-Estrada
  • Eloy Cardenas-Estrada
  • Universidad Autonoma de Nuevo Leon, Centro de Investigacion y Desarrollo en Ciencias de la Salud (CIDICS)/Facultad de Odontología, Calle Dr. Eduardo Aguirre Pequeño s/n, Colonia Mitras Centro, Monterrey, Nuevo Leon, 64460 Mexico.
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  •  Received: 16 July 2018
  •  Accepted: 20 August 2018
  •  Published: 31 August 2018

Abstract

An achievable goal in root canal therapy is to reduce the bacterial population to the lowest level. Irrigation and instrumentation play an important role in achieving this objective. Sodium hypochlorite (NaClO) is the most frequently used irrigation solution; however, its main disadvantage that it is cytoxic to soft tissues following inadvertent extrusion. CatDex is a substance that promises to match the antimicrobial effect of NaClO without being toxic. The aim of the study is to evaluate the in vitro antimicrobial activity of CatDex in doses ranging from 0.17 to 0.05% and compare it with NaClO 5.25, 2.5 and 1.25%, against Porphyromonas endodontalis. P. endodontalis sensitivity to NaClO and CatDex was performed using the disk diffusion method and the minimum inhibitory concentration (MIC). The percentage of P. endodontalis inhibition was 97.8% at 5.25% NaClO and 55% at 0.145% CatDex. CatDex could be considered as a possible alternative for irrigation in root canal therapy. However, more studies are needed to verify its effect and to determine its correct clinical use.

Key words: Porphyromonas endodontalis, root canal, antimicrobial, efficacy, dental disinfectants.