Journal of
Environmental Chemistry and Ecotoxicology

  • Abbreviation: J. Environ. Chem. Ecotoxicol.
  • Language: English
  • ISSN: 2141-226X
  • DOI: 10.5897/JECE
  • Start Year: 2009
  • Published Articles: 197

Full Length Research Paper

Heavy metals and metalloid accumulation in livers and kidneys of wild rats around gold-mining communities in Tarkwa, Ghana

Nesta Bortey-Sam
  • Nesta Bortey-Sam
  • Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Japan.
  • Google Scholar
Shouta M. M. Nakayama
  • Shouta M. M. Nakayama
  • Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Japan.
  • Google Scholar
Yoshinori Ikenaka
  • Yoshinori Ikenaka
  • Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Japan.
  • Google Scholar
Osei Akoto
  • Osei Akoto
  • Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
  • Google Scholar
Elvis Baidoo
  • Elvis Baidoo
  • Department of Chemistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
  • Google Scholar
Hazuki Mizukawa
  • Hazuki Mizukawa
  • Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Japan.
  • Google Scholar
Mayumi Ishizuka*
  • Mayumi Ishizuka*
  • Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Japan.
  • Google Scholar


  •  Received: 25 February 2016
  •  Accepted: 27 May 2016
  •  Published: 31 July 2016

References

Abou-Arab AAK (2001). Heavy metal contents in Egyptian meat and the role of detergent washing on their levels. Food Chem. Toxicol. 39(6):593-599.
Crossref

 

Akabzaa T, Darimani A (2001). Impact of mining sector investment in Ghana: a study of the Tarkwa mining region. Health Impacts 6(4):60.

 

Alfven T, Elinder CG, Carlsson MD, Grubb A, Hellstrom L, Persson B, Pettersson C, Spång G, Schütz A, Järup L(2000). Low-level cadmium exposure and osteoporosis. J. Bone Miner. Res. 15:1579-1586.
Crossref

 

Amonoo-Neizer EH, Nyamah D, Bakiamoh SB (1995). Mercury and arsenic pollution in soil and biological samples around mining towns if Obuasi, Ghana. Water Air Soil Pollut. 91:363-373.
Crossref

 

Asante KA, Agusa T, Subramanian A, Ansa-Asare OD, Biney CA, Tanabe S (2007). Contamination status of arsenic and other trace elements in drinking water and residents from Tarkwa, a historic mining township in Ghana. Chemosphere 66:1513-1522.
Crossref

 

ATSDR (2013). Agency for Toxic Substances and Disease Registry. Minimum risk levels (MRLs). 

 

Barhoumi R, Faske J, Liu X, Tjalkens RB (2004). Manganese potentiates lipopolysaccharide-induced expression of NOS2 in C6 glioma cells through mitochondrial-dependent activation of nuclear factor kappaB. Mol. Brain Res. 122:167-179.
Crossref

 

Battaglia A, Ghidini S, Campanini G, Spaggiari R (2005). Heavy metal contamination in little owl (Athene noctua) and common buzzard (Buteo buteo) from northern Italy. Ecotoxicol. Environ. Saf. 60:61-66.
Crossref

 

Berglund M, Akesson A, Nermell B, Vahter M (1994). Intestinal absorption of dietary cadmium in women depends on body iron stores and fiber intake. Environ. Health Perspect. 102:1058-1066.
Crossref

 

Blagojevic J, Jovanović V, Stamenković G, Jojić V, Bugarski-Stanojević V, AdnaÄ‘ević T, Vujošević M (2012). Age differences in bioaccumulation of heavy metals in populations of the black-striped field mouse, Apodemusagrarius (Rodentia, Mammalia). Int. J. Environ. Res. 6(4):1045-1052.

 

Bortey-Sam N, Nakayama SM, Akoto O, Ikenaka Y, Baidoo E, Mizukawa H, Ishizuka M (2015a). Ecological Risk of Heavy Metals and a Metalloid in Agricultural Soils in Tarkwa, Ghana. Int. J. Environ. Res. Public Health 12(9):11448-11465.
Crossref

 

Bortey-Sam N, Nakayama SM, Akoto O, Ikenaka Y, Fobil JN, Baidoo E, Mizukawa H, Ishizuka M (2015c). Accumulation of heavy metals and metalloid in foodstuffs from agricultural soils around Tarkwa area in Ghana, and associated human health risks. Int. J. Environ. Res. Public Health 12(8):8811-8827.
Crossref

 

Bortey-Sam N, Nakayama SM, Ikenaka Y, Akoto O, Baidoo E, Mizukawa H, Ishizuka M (2015b). Health risk assessment of heavy metals and metalloid in drinking water from communities near gold mines in Tarkwa, Ghana. Environ. Monit. Assess. 187(7):1-12.
Crossref

 

Bortey-Sam N, Nakayama SM, Ikenaka Y, Akoto O, Baidoo E, Yohannes YB, Mizukawa H, Ishizuka M (2015d). Human health risks from metals and metalloid via consumption of food animals near gold mines in Tarkwa, Ghana: Estimation of the daily intakes and target hazard quotients (THQs). Ecotoxicol. Environ. Saf. 111:160-167.
Crossref

 

Brzoska MM, Majewska K, Moniuszko-Jakoniuk J (2004). Mineral status and mechanical properties of lumbar spine of female rats chronically exposed to various levels of cadmium. Bone 34(3):517-526.
Crossref

 

Ceruti R, Ghisleni G, Ferretti E, Cammarata S, Sonzogni O, Scanziani E (2002). Wild rats as monitors of environmental lead contamination in the urban area of Milan, Italy. Environ. Pollut. 117:255-259.
Crossref

 

Chen X, Wang G, Li X, Gan C, Zhu G, Jin T, Wang Z (2013). Environmental level of cadmium exposure stimulates osteoclasts formation in male rats. Food Chem. Toxicol. 60:530-535.
Crossref

 

Crossgrove J, Zheng W (2004). Manganese toxicity upon overexposure. NMR Biomed. 17:544-553.
Crossref

 

Damek-Poprawa M, Sawicka-Kapusta K (2004). Histopathological changes in the liver, kidneys, and testes of bank voles environmentally exposed to heavy metal emissions from the steelworks and zinc smelter in Poland. Environ. Res. 92:72-78.
Crossref

 

Daniell HW (1976). Osteoporosis of the slender smoker. Obstet. Gynecol. Surv. 31(11):808-810.
Crossref

 

Dorman DC, Struve MF, Marshall MW, Parkinson CU, James RA, Wong BA (2006). Tissue manganese concentrations in young male rhesus monkeys following subchronic manganese sulfate inhalation. Toxicol. Sci. 92:201-210.
Crossref

 

EC (2006). European Commission Regulation (EC) No 1881/2006 of 19 December 2006 setting maximum levels for certain contaminants in foodstuff. Off. J. Eur. Union.

 

Finley JW (1998). Manganese uptake and release by cultured human hepato-carcinoma (Hep-G2) cells. Biol. Trace Elem. Res. 64:101-118.
Crossref

 

Flanagan PR, McLellan JS, Haist J, Cherian MG, Chamberlain MJ, Valberg LS (1978). Increased dietary cadmium absorption in mice and human subjects with iron deficiency. Gastroenterology 74:841–846.

 

Florea AM, Busselberg D (2006). Occurrence, use and potential toxic effects of metals and metal compounds. Biometals 19(4):419-427.
Crossref

 

Ghana Statistical Service (2010). Population and Housing census. 

 

Godowicz B (1988). Cadmium-induced liver and spleen damage in inbred mouse strains. Folia Biol. 36:47-52.

 

Guerrero-Castilla A, Olivero-Verbel J, Marrugo-Negrete J (2014). Heavy metals in wild house mice from coal-mining areas of Colombia and expression of genes related to oxidative stress, DNA damage and exposure to metals. Mutat. Res Gen. Tox. Environ. 762:24-29.
Crossref

 

Gupta UC (1998). Trace element toxicity relationships to crop production and livestock and human health: implications for management. Commun. Soil Sci. Plan. 29:1491-1522.
Crossref

 

Hamilton DL, Valberg LS (1974). Relationship between cadmium and iron absorption. Am. J. Physiol. 227:1033–1037.

 

Hayford EK, Amin A, Osae EK, Kutu J (2008). Impact of gold mining on soil and some staple foods collected from selected mining communities in and around Tarkwa Prestea Area. West African J. Appl. Ecol. 14:1-12.

 

Homady M, Helmi H, Jiries A, Mahasneh A, AlNasir F, Khleifat K (2002). Survey of some heavy metals in sediments from vehicular service stations in Jordan and their effects on social aggression in prepubertal male mice. Environ. Res. 8 (1):43-49.
Crossref

 

Honda R, Tsuritani I, Noborisaka Y, Suzuki H, Ishizaki M (2003). Urinary cadmium excretion is correlated with calcaneal bone mass in Japanese women living in an urban area. Environ. Res. 91:63-70.
Crossref

 

Hunter BA, Johnson MS, Thompson DJ (1989). Ecotoxicology of copper and cadmium in contaminated grassland ecosystem. 4. Tissue distribution and age accumulation in small mammals. J. Appl. Ecol. 26:89–99.
Crossref

 

Husain A, Al-Rashdan A, Al-Awadhi A, Mahgoub B, Al-Amiri H (1996). Toxic metals in food products originating from locally reared animals in Kuwait. Bull. Environ. Contam. Toxicol. 57:549-555.
Crossref

 

Jarup L (2002). Cadmium overload and toxicity. Nephrol. Dial Transplant 17(2):35-39.
Crossref

 

Kabata-Pendias A, Pendias H (1992). Trace Elements in Soils and Plants, second ed. CRC Press, London, P 413.

 

Kowel NE (1988). Urinary cadmium and beta2-microglobulin: correlation with nutrition and smoking history. J. Toxicol. Environ. Health 25:179–183.
Crossref

 

Licata P, Naccari F, Lo Turco V, Rando R, Di Bella G, Dugo G (2010). Levels of Cd (II), Mn (II), Pb (II), Cu (II), and Zn (II) in Common Buzzard (Buteo buteo) from Sicily (Italy) by Derivative Stripping Potentiometry. Int. J. Ecol. 1-7.
Crossref

 

Lindsay R, Dempster DW, Clemens T, Herrington BS, Wilt S (1984). Incidence, cost, and risk factors of fracture of the proximal femur in the USA. Osteoporosis 1:311-315.

 

Liu J, Liu Y, Goyer RA, Achanzar W, Waalkes MP (2000). Metallothionein-I/II null mice are more sensitive than wild-type mice to the hepatotoxic and nephrotoxic effects of chronic oral or injected inorganic arsenicals. Toxicol. Sci. 55:460-467.
Crossref

 

López-Alonso M, Miranda M, García-Partida P, Cantero F, Hernández J, Benedito JL (2007). Use of dogs as indicators of metal exposure in rural and urban habitats in NW Spain. Sci. Total Environ. 372:668-675.
Crossref

 

Ma WC (2011). Lead in mammals. In Beyer & Meador (Eds.), Environmental contaminants in biota: interpreting tissue concentrations (2nd ed.). New York: CRC Press pp. 595-607.
Crossref

 

Ma WC, Denneman W, Faber J (1991). Hazardous exposure of ground living small mammals to cadmium and lead in contaminated terrestrial ecosystem. Arch. Environ. Contam. Toxicol. 20:266-270.
Crossref

 

Martinez-Finley EJ, Gavin CE, Aschner M, Gunter TE (2013). Manganese neurotoxicity and the role of reactive oxygen species. Free Radic. Biol. Med. 62:65-75.
Crossref

 

Naccari C, Cristani M, Cimino F, Arcoraci T, Trombetta D (2009). Common buzzards (Buteo buteo) bio-indicators of heavy metals pollution in Sicily (Italy). Environ. Int. 35:594-598.
Crossref

 

Nakayama SM, Ikenaka Y, Hamada K, Muzandu K, Choongo K, Teraoka H, Mizuno N, Ishizuka M (2011). Metal and metalloid contamination in roadside soil and wild rats around a Pb–Zn mine in Kabwe, Zambia. Environ. Pollut. 159(1):175-181.
Crossref

 

Nakayama SM, Ikenaka Y, Hamada K, Muzandu K, Choongo K, Yabe J, Umemura T, Ishizuka M (2013). Accumulation and biological effects of metals in wild rats in mining areas of Zambia. Environ. Monit. Assess. 185(6):4907-4918.
Crossref

 

Obiri S (2007). Determination of heavy metals in water from boreholes in Dumasi in the Wassa West District of the Western Region of the Republic of Ghana. Environ. Monit. Assess. 130:455-463.
Crossref

 

Pereira R, Pereira ML, Ribeiro R, Gonçalves F (2006). Tissues and hair residues and histopathology in wild rats (Rattus rattus L.) and Algerian mice (Mus spretus Lataste) from an abandoned mine area (Southeast Portugal). Environ. Pollut. 139:561-575.
Crossref

 

Pompe-Gotal J, Crnic AP (2002). Cadmium in tissue of roe deer (Capreolus capreolus) in Croatia. Vet. Arh. 72:303-310.

 

Saville PD, Nilsson BE (1966). Height and weight in symptomatic postmenopausal osteoporosis. Clin. Orthop. Relat. Res. 45:49-54.
Crossref

 

Sawicka-Kapusta K, Zakrzewska M, Kowalska A, Lenda B, Skrobacz M (1995). Heavy metal

 

Scheuhammer AM (1987). The chronic toxicity of aluminium, cadmium, mercury, and lead in birds: A review. Environ. Pollut. 46:263-295.
Crossref

 

Soewu DA, Agbolade OM, Oladunjoye RY, Ayodele IA (2014). Bioaccumulation of heavy metals in cane rat (Thryonomys swinderianus) in Ogun State, Nigeria. J.Toxicol. Environ. Health Sci. 6(8):154-160.
Crossref

 

Swiergosz R (2001). Cadmium distribution and toxicity in tissues of small rodents. Microsc. Res. Tech. 55:208-222.
Crossref

 

Taguchi T, Suzuki S (1981). Influence of sex and age on the biological half-life of cadmium in mice. J. Toxicol. Environ. Health 7:239–249.
Crossref

 

Tohyama C, Sugihira N, Saito H (1987). Critical concentration of cadmium for renal toxicity in rats. J. Toxicol. Environ. Health 22:255-259.
Crossref

 

Uriu K, Morimoto I, Kai K, Okazaki Y, Okada Y, Qie YL, et al. (2000). Uncoupling between bone formation and resorption in ovariectomized rats with chronic cadmium exposure. Toxicol. Appl. Pharmacol. 164:264-272.
Crossref

 

USEPA (United States Environmental Protection Agency) (2004). Framework for Inorganic Metals Risk Assessment; USEPA: Washington, DC, USA.

 

USEPA (United States Environmental Protection Agency) (2012). Ground water and drinking water. 

 

Waalkes MP, Ward JM, Liu J, Diwan BA (2003). Transplacental carcinogenicity of inorganic arsenic in the drinking water: induction of hepatic, ovarian, pulmonary, and adrenal tumors in mice. Toxicol. Appl. Pharmacol. 186:7-17.
Crossref

 

Whelton BD, Peterson DP, Moretti ES, Dare H, Bhattacharyya MH (1997). Skeletal changes in multiparous, nulliparous and ovariectomized mice fed either a nutrient-sufficient or -deficient diet containing cadmium. Toxicology 119:103-121.
Crossref

 

WHO (World Health Organization) (1981). Environmental Health Criteria 18. Arsenic. International Programme on Chemical Safety.World Health Organization, Finland.

 

WHO (World Health Organization) (1996). Trace Elements in Human Nutrition and Health. Geneva.

 

WHO (World Health Organization) (2011). Guidelines for drinking-water quality. Geneva

 

Wronski TJ, Schenk PA, Cintron M, Walsh CC (1987). Effect of body weight on osteopenia in ovariectomized rats. Calcif. Tissue Int. 40(3):155-159.
Crossref