Journal of
Infectious Diseases and Immunity

  • Abbreviation: J. Infect. Dis. Immun.
  • Language: English
  • ISSN: 2141-2375
  • DOI: 10.5897/JIDI
  • Start Year: 2009
  • Published Articles: 94

Full Length Research Paper

Pattern of default among tuberculosis patients on directly observed therapy in rural primary health care centres in Ogun State, Nigeria

Amoran O. E.1*, Osiyale O. O.2 and Lawal K. M.3
1Department of Community Medicine and Primary Care, College of Health Sciences, Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria. 2General Hospital, Ijebu-Igbo, Ogun State, Nigeria. 3Disease Control and Primary Health Care, Ogun State Ministry of Health Abeokuta, Ogun State, Nigeria.
Email: [email protected]

  •  Accepted: 25 March 2011
  •  Published: 31 May 2011


This study was designed to identify risk factors associated with defaulting during TB treatment and indicate specific adjustments to be made. This study is a retrospective, cohort study. Information on all TB patients attending clinic for treatment from 1st April 2004 to 30th June 2007 was collected using a data collection form. A total sample of 938 patients was reviewed. The overall default rate among the TB patients was 14.4% and was about half (44.3%) of the entire negative outcome. 743 (79.2%) of cases were cured or completed treatment and 9 (1.0%) of cases were transferred out. Factors associated with default were return after default (p = 0.000), presentation with extra-pulmonary TB (p = 0.000) and defaulting in the first two months of treatment (p = 0.00). There was no statistically significant difference in the rate of default between HIV positive and HIV negative TB patients (22.8% vs 10.5%, X2 = 0.15, p = 0.699) and distance of domicile from PHC centres (p = 0.91). This study suggest that National TB control programmes should pay a closer attention to the issue of home visit and monitoring especially among  patients with smear-negative PTB or EPTB and those returning after default in African population.


Keywords: Tuberculosis,default rate,primary health care,directly observed theraphy.