Journal of
Infectious Diseases and Immunity

  • Abbreviation: J. Infect. Dis. Immun.
  • Language: English
  • ISSN: 2141-2375
  • DOI: 10.5897/JIDI
  • Start Year: 2009
  • Published Articles: 94

Full Length Research Paper

A cost effectiveness analysis of the H1N1 vaccine strategy for Ontario, Canada

A. Durbin1,4, A. N. Corallo1, T. G. Wibisono2, D. M. Aleman2,4, B. Schwartz3 and P. C. Coyte1,4*
1Dalla Lana School of Public Health, University of Toronto, Ontario, Canada. 2Mechanical and Industrial Engineering Department, University of Toronto, Ontario, Canada. 3Ontario Agency for Health Protection and Promotion, Ontario, Canada. 4Department of Health Policy, Management and Evaluation, University of Toronto, Ontario, Canada. 5Department of Family and Community Medicine, University of Toronto, Ontario, Canada.
Email: [email protected]

  •  Accepted: 01 February 2011
  •  Published: 31 March 2011


In Ontario, Canada, a mass vaccination strategy was developed and implemented to mitigate the effects of the 2009 pandemic influenza A (pH1N1). This study investigated its cost-effectiveness, mirroring actual events in Ontario, compared to no vaccine strategy. From a societal perspective, 1,780,491 cases and 154 deaths were averted through vaccine administration; the incremental cost effectiveness ratio predicted that the vaccination program saved $117 per case avoided, or $1.35 million per death averted, for total savings of $208.3 million. From a government perspective (Ontario Ministry of Health and Long Term Care) this strategy required an expenditure of $28 per case averted and $0.33 million per death averted, for a total cost of $252.4 million.


Key words: Cost effectiveness, H1N1, Ontario, pandemic influenza, vaccine.