To study HLA-DQA1 genotyping in Helicobacter pylori associated gastritis patients. This study was carried out in College of Medicine, University of Basrah. HLA-DQA1 genotyping was done in College of Medicine, University of Manitoba, Winnipeg, Canada during the period from 17th of April 2009 to 15th of July 2010. A total of 100 patients (41 males and 59 females and a total of 30 controls (18 males and 12 females) were included in this study. DQA1 alleles frequencies were studied in 70H. pylori associated gastritis patients and 30 healthy controls. DQA1*0201 decreased allele frequency was statistically not significant in H. pylori associated gastritis patients, but there was a strong association (odds ratio= 2.61(, as compared with controls. In the present study many alleles from both locus showed high frequencies with a very strong association, but statistically not significant, this association has not been reported and it is important to note that a larger sample size should be studied.
Key words: HLA-DQA1 genotyping, DQA1*0201, Helicobacter
Copyright © 2021 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0