Journal of
Medical Laboratory and Diagnosis

  • Abbreviation: J. Med. Lab. Diagn.
  • Language: English
  • ISSN: 2141-2618
  • DOI: 10.5897/JMLD
  • Start Year: 2010
  • Published Articles: 55

Full Length Research Paper

Percutaneous needle biopsy in the diagnosis of soft tissue tumors – A potent tool in underdeveloped countries

Jaseem Hasan
  • Jaseem Hasan
  • Hamdard Institute of Medical Sciences and Research, New Delhi, India.
  • Google Scholar
S. Shamshad Ahmad
  • S. Shamshad Ahmad
  • Departments of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India.
  • Google Scholar
Kafil Akhtar
  • Kafil Akhtar
  • Departments of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India.
  • Google Scholar
Shaista M. Vasenwala
  • Shaista M. Vasenwala
  • Departments of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India.
  • Google Scholar
Mehar Aziz
  • Mehar Aziz
  • Departments of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, India.
  • Google Scholar


  •  Accepted: 30 May 2012
  •  Published: 30 November 2012

Abstract

Fine needle aspiration biopsy is a useful tool in the pre-operative evaluation and grading of soft tissue tumors, and offer patients the advantage of neo-adjuvant/ adjuvant chemotherapy or radiotherapy. Our study aimed at correlating the clinical, radiological and cytological findings of benign and malignant tumors of soft tissues and evaluating the usefulness of percutaneous needle biopsy as a diagnostic tool. Out of a total of 136 cases of soft tissue tumors aspirated, 110 were benign and 26 malignant. Upper extremity including axilla was the most frequently involved site of benign soft tissue tumors with 37 cases, while the lower extremity including inguinal area was the most common site of malignant soft tissue tumors with 10 cases. Sensitivity and specificity of cytological diagnosis was 77.8 and 92.3%, respectively, while the positive and negative predictive value was 87.5 and 86.7%, respectively, with the diagnostic accuracy being 86.9%.

 

Key words: Fine needle aspiration biopsy, soft tissue tumors, immunohistochemistry.