December 2018
Ethnobotanical study of indigenous knowledge on medicinal plants used to treat diseases in selected districts of Amhara Regional State, Ethiopia
This study was conducted in four districts of Amhara Region, Ethiopia. The aim of the study was to assess medicinal plants found in Menz gera, Siyadebirna Wayu, Antsokiya gemza and Bugna districts, Amhara region, Ethiopia. The ethnobotanical surveys were carried out from September 2017 to June 2018 using a semi-structured checklist consisting of questions or issues prepared in advance. Two separate questionnaires were...
December 2018
Selenium-enriched polysaccharides from pyracantha fortuneana (Se-PFPs) augment docetaxel-induced tumor suppression in human ovarian cancer
Pyracantha fortuneana (Maxim.) contains many healthy ingredients, including selenium-enriched polysaccharides. Selenium-enriched polysaccharides from P. fortuneana (Se-PFPs) have anti-mutation and anti-oxidation activities, along with anti-tumor activity in ovarian cancer and breast cancer cells. Docetaxel (DTX) is widely applied in therapeutic treatment for ovarian cancer. However, its use in clinics is restricted due...
December 2018
Comparative analysis of capsaicin in twenty nine varieties of unexplored Capsicum and its antimicrobial activity against bacterial and fungal pathogens
In this study, the capsaicin content of chile pepper extracts from 29 unexplored varieties of Capsicum (twenty five varieties of Capsicum chinense and five of Capsicum annuum) was quantified and correlated with the antimicrobial potential against bacterial and fungal pathogens. The capsaicin content and bactericidal activity against numerous human pathogens (Salmonella, Escherichia coli O157:H7, Listeria monocytogenes,...
December 2018
Hepato-protective potentials of Sterculia setigera stem-bark extract on acetominophen induced hepato toxicity in Wistar albino rats
The study was set to investigate the potency of stem bark extract of Sterculia setigera as a hepato-protective agent against acute administration (overdose) of acetaminophen in experimental animals. Experimental animals were grouped into six treatments with each group containing five rats. Group 1 was the placebo, Group II was the standard treatment orally administered acetaminophen at a dosage of 250 mg/kgbw and...
December 2018
Phytochemical analysis, antioxidant, antibacterial and combinational effects of medicinal plants used by Bapedi traditional healers to prepare herbal mixtures
The aim of this study is to evaluate the biological activities of some plant species used in the preparation of herbal mixtures and determine the combinational effects. The plant materials were collected from traders who use them to prepare herbal mixtures claimed to be blood purifiers, pain-relievers, anti-diarrheal and aphrodisiac medicines. An aqueous decoction of each plant species was prepared. Thin layer...
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