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Background: Pechuel-Loeschea leubnitziae is a predominant medicinal plant in Namibia. It’s traditionally utilized in treatment of gastrointestinal issues, sexually transmitted infections and common cold. Despite its therapeutic potential, the phytochemicals profile and compounds composition are yet to be scientifically validated. Objective: This study was conducted to determine the spectrum and total phytochemical...
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Plants have long been a source for a wide variety of compounds with medicinal properties. Of significant interest are plant antimicrobial compounds. Given the continual increase of bacterial resistance, it is imperative that new antimicrobial compounds need to be discovered. The purpose of this study was to screen some common household plants for antibacterial activity, specifically against Escherichia coli (E. coli)....
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Due to the action of essential oils of thyme, lemongrass and rosemary against microorganisms and little studies about these essential oils on vegetable seed treatment, the aim of this study was to evaluate the effect of the treatment with these essential oils on cauliflower seeds inoculated with A. flavus and the effect in the physiological and sanitary quality. Cauliflower seeds inoculated with the fungus Aspergillus sp....
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This study focuses on testing the efficacy of herbal remedy used in many homes within the South-Eastern part of Nigeria to treat malaria and also the histopathological effect of the remedy on albino rats. Twenty rats were procured and distributed with five rats to one group. Group 1 received Garcinia kola and Aloe vera extracts, Group 2 received only Garcinia kola extract, Group 3 is negative control and Group 4 is...
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The use of medicinal plants as alternative therapy for the treatment of microbial infections is significant in the maintenance of good health, especially in developing countries. The aim of this study was to determine the phytochemical composition and antimicrobial activity of B. coriacea and P. microphylla leaf extracts on bacteria isolated from aquatic environments in Nigeria. Exactly 736 water samples from boreholes,...
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Alcohol withdrawal syndrome (AWS) is a common medical problem that can occur as a result of reducing or cessation of alcohol consumption and lead to alcoholic relapse. The objective of the present study is to investigate the neuroprotective effect of an acetone water extract from Moroccan Cistus Monspeliensis (CM) against the development of AWS and its associated disorders. To study AWS related disorders and possible...
Medicinal Plants with Potential to Regulate Male Fertility
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The strain on our environment due to increase in population is a major threat to the goals of sustainable development. The need to control population growth for conserving natural resources has led us to explore methods to control population. The best method to control population is to encourage and educate people about various contraceptive methods. There are various methods and technologies that are used to overcome this...
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The nutraceutical composition of Sarcodon sp, a wild edible mushroom has outstanding biological activities. However, up to now, not enough nutraceutical information has been reported for this fungus in Mexico, that is, about its preventive and/or therapeutic capacity. The purpose of this work was to describe taxonomically this mushroom and to determine total phenolic contents as equivalents of gallic acid, phenolics acids...
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Diabetic ulcers are a severe complication in patients with diabetes that often lead to amputation. The etiology of diabetes-induced wound healing impairment is multi-faceted. Persistent inflammation and deficient tissue regeneration have been suggested to impair wound healing in diabetes patients. Although new therapeutic approaches have been developed, many chronic wound treatments remain unsatisfactory, and more...
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The documentation of medicinal uses of plants is becoming increasingly urgent because of the rapid loss of the natural habitat for some of these plants due to anthropogenic activities. Traditional knowledge of medicinal plants is also at risk of extinction due to the dependency on oral transmission, and as such, there is an urgent need to document such knowledge. The study aimed at document medicinal plants used in the...
Endophytic Aspergillus sp. Isolated from leaves of Mangifera indica, and its Biological activities
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Endophytic compounds from Nigerian plants is of significant interest in the search for drug compounds possibly due to their potentials to contribute new compounds with biological properties in the fight against drug resistance pathogens. Consequently, this study was embarked upon to investigate the bioactivities of secondary metabolites of endophytic Aspergillus sp. isolated from the leaves of Mangifera indica. Fresh...
In Vitro Antioxidant and Anti-diabetic Activities of Carica papaya Seed Extracts
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Carica papaya seeds have been reported in folklore medicine as a remedy used in treating diabetes mellitus without a proper documented possible mode of action. This study aimed at evaluating antioxidant and anti-diabetic activities of Carica papaya seed extracts in vitro. The air-dried ripe seeds were coarsely powdered and extracted via the soxhlet method to obtain their crude extracts. The crude extracts were then...
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Most of the wet land area either remains unutilized or underutilized for cultivation and conservation of economic species. The area either remains covered by means of weeds or unmanaged as such lies useless. The present article introduces a model of ‘Aquatic herbal garden’ developed by Herbal research and development Institute (HRDI) at its camps in Mandal area to utilize such partially or fully waterlogged area to grow...
Assessment of Active Components from Invasive Alien Plant Species Distributed in Bihar
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Plant pathogenic microbes are on rise and thus causing plants quality deterioration. Use of chemicals to lessen their effect, knowingly or unknowingly leaves their side effects. Natural product, a suitable alternative as antimicrobial agent to curb effect of such plant pathogenic microbes has led to study many rare and uncommon plants. Our study aimed to find some active constituents from invading alien species (IAS)...
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Fungal endophytes are regarded as inexhaustible sources of pharmaceuticals and agrochemicals with profound antibacterial, anticancer or antifungal activities. Diaporthe sp, an endophytic fungus residing in medicinal plant S. cordatum, showed a good antagonism against bacterial pathogens of beans; Pseudomonas syringae pv phaseolicola (Psp) and Xanthomonas axonopodis pv phaseoli (Xap), with zones of inhibitions of 14.00 ±...
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It was reported in 2005 during WHO survey that about 70-80% of the world population use medicinal plants either in their crude unmodified form or partially in their modified semi-synthetic form of plant sources in their primary healthcare. The present study investigated the phytochemicals and antimicrobial activities of the leaf extracts of Cerathoteca sesamoides and Chromolaena odorata to ascertain their potentials in...
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Leishmaniasis is the second-largest parasitic killer in the world (after malaria).Currently, there are no effective vaccines or therapeutic interventions thus creating a gap for new alternative remedies in the management of the disease. Medicinal plants offer this attractive option as antileishmanial agents since they are relatively safe, locally available and affordable. The study assessed antileishmanial activity of...
Levels of heavy metals in four malawian medicinal plants used for treatment of infectious diseases
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Medicinal plants could potentially be contaminated with heavy metals during growing in the field, processing and/or handling. These heavy metals may be toxic to humans and cause damage to organs such as liver, kidneys and lungs. Currently, there is no data available on the levels of heavy metals in medicinal plants traditionally used for management of infectious diseases in Malawi. The aim of this study was to determine...
Technical feasibility of products based on camu-camu (Myrciaria dubia): a review.
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Camu-camu (CC) is a fruit from the Amazon that has been well studied and has great therapeutic potential. The present study was aimed at reviewing botanical, phitochemical and processing aspects of this fruit, in addition this biological effect. Results: Despite the amount of information available regarding this fruit and the potential use of this plant, the market lacks products based on camu-camu. This work summarizes...
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The aim of this study was designed to evaluate the effect of Berberis vulgaris water extract (BWE) against CCl4-induced hepatotoxicity and LPS/PCM induced- hepatic inflammation in the experimental animal models. CCl4 (100ug/kg, oral) administration for 28 days as well as the co- administration of LPS (250ug/kg bw) and PCM (2g/kg bw) for 28days resulted in massive elevation in serum and hepatic prooxidants and inflammatory...
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This study evaluated the anti-hyperglycemic potential of Stemonocoleus micranthus Harms. (Fabaceae) stem bark.Three models used in this study were: normoglycemic animal model, oral glucose tolerance test (OGTT) and alloxan-induced hyperglycemic model for acute and prolonged administration. Five (5) groups of rats (n=6) were used for all models; group 1 served as the control while groups 2, 3, and 4 received S. micranthus...
Anti-bacterial activity of secondary metabolites from Chrysanthemum cinerariaefolium
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Mortality and morbidity due to bacterial infections continue to threaten humanity in the 21st century. Bacterial resistance to current antibiotics due to overuse has necessitated a search for new alternative novel drugs that are less prone to resistance. This study evaluated antibacterial activity of Chrysanthemum cinerariaefolium (pyrethrum) flower extracts, fractions and isolated compounds which included pyrethrin II,...
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Neurodegenerative diseases refer to physiological changes leading to death of nerve cells present in the brain and spinal cord. Current treatment for this disease is not effective and caused many side effects. Thus, the search for alternative medicines is in high demand. Therefore, the aim of this study is to evaluate the anti-cholinesterase properties of Phaleria macrocarpa (leaf). Bioactive compounds from Phaleria...
Insecticidal effect of Hyptis suaveolens chemotype 1,8- cineole on lice, poultry parasites
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Aromatic plants can provide potential alternative solutions to synthetic molecular currently used in the control of poultry ectoparasites because they are a rich source of bioactive chemicals. The purpose of this study is therefore to analyze the chemical constituents of the essential oil of H. suaveolens and to evaluate the insecticidal effect on lice parasite in chicken and turkey. A gas chromatographic analysis...
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Diabetes affects 422 million people in the world and caused 1.5 million deaths. The Psydrax genus has been reported to have various pharmacological activities. Based on ethno-pharmacological information, Psydrax horizontalis Schum. & Thonn. (Bridson) locally known as “Akata-ike” in Nsukka is used in the management of diabetes in South-eastern Nigeria. However, as at the time of this research, no previous work has been...
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Traditional medicine is used in all over the world, especially in developing countries. Though synthetic drugs are very effective but are harmful to human beings because of their side effects. Genus of Terminalia and Combretum species are belong to the family Combretaceae, which contains 20 genera and 600 species as herbs, shrubs and trees. These plants are used in different traditional medicine for their antioxidant...
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In Ethiopia, many plants are used for medicinal purpose by traditional healers without any scientific justification for their therapeutic values. The principal Aim of this study were to evaluate the in vitro antibacterial and antifungal activities of the leaf, root and stem bark extracts of Rhamnus prinioides (gesho), Justicia schimperiana (sensel) and Ruta chalepensis (Tena adam) against some common pathogenic species of...
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The concentrations of essential macro and micro elements were determined using Energy Dispersive X-ray Fluorescence technique (EDXRF) being the most suitable instrument for the multi-element analysis in plant samples. Two macroelements (Ca and K) and seven microelements (Fe, Mn, Zn, Cu, Rb, Sr and Br) were analyzed in different parts (leaves, wood bark and roots) of Durio zibethinus Murr. The results revealed the levels of...
Antiurolithiatic Activity of Selected Plants Extracts Against Calcium Oxalate Crystals
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The present study was designed to evaluate the antiurolithiatic activity of selected plants extracts (Achyranthes aspera, Lawsonia inermis, Ficus benghalensis, Raphnus sativus and Macrotyloma uniflorum) against calcium oxalate crystals. The methanol extract of selected plants was analysed for in-vitro antiurolithiatic activity using nucleation, aggregation and growth assay of calcium oxalate (CaOX) monohydrate crystals....
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Reports from extensive surveys have indicated that about 70-80% of the world population; particularly in the developing countries rely on non-conventional medicine mainly of herbal origins for their primary health care. Correct identification and quality assurance of the starting materials are essential prerequisites to ensuring reproducible quality of herbal medicine which will contribute to its safety and efficacy. This...
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Plant part such asleaves, stems, branches, twigs, and roots possess different therapeutic functions and activities. Besides that, development stages, either young or mature could cause several effects to the bioactive compounds as well as the antioxidant properties of the plant. Thus, an experiment was conducted using a nested design, with three replications, involved young and mature development stages and three different...
ETHNOMEDICINAL EVALUATION OF SOME ANTIMALARIAL PLANTS USED IN ONDO STATE, NIGERIA
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The use of herbs and plant materials have always been popular in the treatment of febrile illness, and it has grown over time in malaria endemic areas. Structured questionnaires were administered in four towns in each of the three senatorial districts of Ondo state to know the most commonly used herbs and the results suggested Mango (Mangifera indica) Siam weed (Chromolaena odorata) and Guava (Psidium guajava) as most...
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Antifungal activity of the ethanolic extract of Alchornea cordifolia plant was evaluated both in vitro and in vivo against Aspergillus fumigatus, and Aspergillus terreus, mostly implicated in plant and animal fungal diseases. Antifungal potential of the extract were evaluated quantitatively in vitro using well diffusion method and in vivo by studying the survival rate of Drosophila melanogaster (Harwich) challenged with...
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Hyper pigmentation is skin disorders affect the color of skin that may require treatment. There are many chemical agents to treatment of hyper pigmentation such as hydroquinone, retinoids and other agents but do not satisfactory results and may be highly morbid. In addition to consumer prospective natural origin is more acceptable with mush less contraindication. Soybean derived peptides have demonstrated numerous...
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Plant-based foods have health benefits and minimal side effects than synthetic anti-diabetic agents. Therefore, this study evaluated nutritional and anti-hyperglycaemic efficacies of raw African star apple (RASA) and fermented African star apple seeds (FASA). Methodology: The RASA and FASA seeds were processed into flour, and nutritional qualities, antioxidative and antidiabetic activities in wistar rats were evaluated at...
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The stem bark of Piptadeniastrum africanum (Hook. F.) (syn. Piptadenia Africana) Brenan (Mimosaceae) is used in Cameroonian and Gabonese folk medicine for the relief of some painful sicknesses. This study was intended to evaluate the analgesic and anti-inflammatory activities of the aqueous extract of P. africanum. The analgesic investigations were carried out against acute noxious stimuli, that are chemical (acetic...
Ethno Botanical Perspective of Medicinal Plants in Mulkhow Valley District Upper Chitral, Pakistan
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This paper demonstrates the ethnobotanical perspectives of medicinal plant in Mulkhow valley, district Chitral. The main aim of this research work was to gather information to document the medicinal uses of plants in Mulkhow valley. The results of ethnobotanical perspective contain quantitative information of medicinal plants used by indigenous people in Mulkhow valley. The current study conducted between 2015 – 2016...
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Globally, medicinal plants have been used to treat different human ailments from time immemorial. In Kenya, various plants are used by local people in the treatment of various diseases.This is a common practice in Nandi county due to scarce health facilities in the region, traditional beliefs, cultural barriers and availability of medicinal plants. The objective of this study was to carry out an ethnobotanical survey to...
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Medicinal plants have bioactive compounds which are used for curing of various human diseases and also play an important role in healing. Phytochemicals have two categories. These are primary and secondary constituents. Primary constituents have chlorophyll, proteins sugar and amino acids. Secondary constituents contains like terpenoids, flavonoids, saponins, tannins, alkaloids, glycosides and phenols. Secondary...
Antibacterial and Antioxidant Compounds from the Tubers Extracts of Plectranthus edulis
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P. edulis is an indigenous plant which has been cultivated for its edible tuber. It is claimed to have antibacterial activity. But this was not supported by scientific investigation. Hence this work explores the antibacterial and antioxidant activities of extracts and isolated compounds from the tuber of P. edulis. The effects of the extracts and isolated compounds of tubers of P. edulis were evaluated against S. aureus,...
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Ethiopia has numerous plants that can be used as sources of medicine for those who cannot access modern health care. This study was conducted to document the indigenous knowledge and medicinal plants in and around Ambo town. The study was carried out from April to August 2018. A total of 49 participants were selected randomly from the representative kebeles. Twenty two medicinal plants were collected and documented based...
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Boscia senegalensis and Tapinanthus dodoneifolius are two plants mostly used by herders to treat animal diseases in the Far North Region of Cameroon. To evaluate the in vitro antibacterial, cytotoxic and antioxidant potentials of these plants. To achieve this, five extracts (water, methanol, chloroform and hexane) of both plants obtained by successive fractionation were used. Antibacterial activities of the different...
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ABSTRACT The investigation of traditional medicinal plants was performed in Bale district from August to October 2018 in three kebeles Kedu, Elasa and Aloshe Tilo. In the study area diverse medicinal plant were used to treat many human and livestock disease. The data were collected from the informants through semi-structured interview, discussion and collected plant samples from the study areas that were used to treat...
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Aristolochia ringens (Vahl) and Securidaca longepedunculata Fresens are used in traditional African medicine for the treatment of arthritis, diarrhoea, asthma, snakebites and skin rashes. This present study examines the acute and sub-acute toxicity effects of these plants in rats. The animals (5 per group) were treated daily with the extract at doses of 100, 250, 500 mg/kg orally for 28 days. Control group received...
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Large cardamom (Amomum. subulatum Roxb) commonly known as a badi elaichi, is a tall, perennial, evergreen, herbaceous monocot plant. Large cardamom is well known spice, which has medicinal value. The present study has been designed to explore the base line morphological characteristics, chemo-profile, to raise superior quality planting materials through micro propagation and large cardamom farming as an appropriate...
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An ethnobotanical study of traditionally used medicinal plants to trat human disease was conducted in Goba District of Bale Zone, Ethiopia. Information was gathered from 60 informants using semi-structured interview. For data collection the site and the informants were selected purposivelly. During the study, a total of 42 medicinal plant speceis belonging to 24 families were recorded. The family Euphorbiaceae has four...
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Investigation was carried out on the effects of 50mg/mL and 100mg/mL concentration of methanol and omidun extracts of root of V. paradoxa on hematological parameters of diarrhea induced albino rats. A total of 5 test organisms ((Shigella dysenteriae, Salmonella typhi, Escherichia coli ATCC 25922,Enteropathogenic Escherichia coli ‘EPEC ATCC 43887’, Enterohemorrhagic Escherichia coli ‘EHEC ATCC 43889’) associated with...
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Studies on the medicinal (hypoglycemic) potential of Magnifera indica (M. indica) have been documented. However, little may still be known about the dose level and the effects it may have on haematocrit, liver enzymes and body weight of a diabetic individual. The present study was designed to investigate the hypoglycemic effect of aqueous M. indica leaves extract on alloxan-induced diabetes in albino rats Rattus rattus....
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This study evaluated the phytoconstituents of the chloroform extract of Chasmenthera dependens (C. dependens) roots and the effect of the extract on the liver serum/homogenate enzyme activities of carbon Tetrachloride Induced hepatoxicity in Wistar Albino Rats. Twenty-four (24) female albino rats were used for this study and were divided into groups of four rats each: Groups I rats were normal control. Hepatotoxicity was...
A Review of the Ethnomedicinal uses of pteridophytes for treating various human ailments in India
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Pteridophytes present significant evolutionary innovations such as development of true conducting system with xylem and phloem and dominant saprophytic phase. Pteridophytes are frequently used as ornamental plants because of the green long lasting large foliage and sturdy plant forms. They are being used as bio-indicators for pollution, phytoremediators, and some used as bio-fertilizers. During the invasion of land...
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