Article in Press
Ocimum gratissimum essential oil (EOGT) has been evaluated for its antibacterial efficacy, and its combinatorial therapy with antibiotics may enhance the therapeutic efficiency against infection-causing bacteria. Herein, we evaluated the chemical composition of EOGT and its antibiotic efficacy against Staphylococcus aureus and Pseudomonas aeruginosa. GC-MS and GC-FID analyzed EOGT. The antibiotic efficacy was determined by...
Article in Press
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been identified as the agent responsible for the COVID-19pandemic. Currently no therapeutic agents or vaccines that have proven effective in combating the virus. Management of the infection is mainly palliative in nature and involves strategies such as prevention of the infection and, supportive therapy anchored on drugs with that practitioners have had...
Evaluation of the in vitro toxicological potential of crude Piper aduncum extract
Article in Press
Several substances derived from plant metabolism appear to have therapeutic effects, requiring toxicity and mutagenicity studies to determine their safe use capable of producing a satisfactory effect of the drug. Reports in the literature demonstrate that ethanolic extracts of P. aduncum leaves have antiprotozoal, antimalarial and insecticidal activity. The present study aimed to conduct pre-clinical toxicological tests of...
Phytochemical investigation of prosopis juliflora leaves extracts and their insecticidal activity
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One known compound trans-ferrulate (compound 1) together with fatty acids derivatives were isolated from the leaves of plant Prosopis juliflora. It is an invasive plant found in dry regions of Kenya mainly Baringo, Turkana, Tana river and other regions. The plant has been reported to possess many phytochemicals, some of which are assumed to possess insecticidal activities. The leaves were collected from Baringo County,...
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The African Walnut plant is a climber which grows mainly in Nigeria and Cameroun. It is a lesser-used oil plant with probable efficacy for treating proliferative diseases. This study investigated the antioxidant properties of African walnut seed oil (AWSO) on Dimethyl nitrosamine (DMN) induced liver injuries in Wistar rats. The AWSO was extracted with n-hexane using the Soxhlet apparatus. Sets of 30 Wistar rats in 6 groups...
Article in Press
The study was undertaken with the general objective of providing documentation of traditional medicinal plants (MPs), and associated indigenous knowledge of the people inhabiting in and around Aba-Asrat Monastery, East Gojjam Zone, North western Ethiopia. Ethnobotanical data were collected using semi-structured interviews, observation and focus group discussions in the field. A total of 160 (100 males and 60 females)...
Article in Press
Traditional medicine is used by people as an alternative to orthodox drugs to treat respiratory infections. The aim of this research was to document traditional recipes used in the treatment of upper respiratory tract infections such as pharyngitis, cold, and sinusitis in peri-urban and rural areas of the Littoral Region of Cameroon. Ethnobotanical surveys were carried out using semi-structured interview model in French or...
Article in Press
The present study focuses on the phytochemical composition and in vitro and in vivo antioxidant properties of A. senegalensis root bark. Phenolic total compounds and tannins were quantified by Folin-Ciocalteu, and flavonoids by described by Arvouet-Grand et al. Alkaloids were determined using atropine as a reference. For antioxidant activities, FRAP assay; DPPH, RPA, and RHS were evaluated by standard methods. Thus, A....
Article in Press
Background: Currently, there is an upsurge of bacterial resistance in single-drug treatment regimens. This has stimulated a growing interest in research and development of new antibacterial agents containing several ingredients as one of the means to combat bacterial resistance. Herb-antibiotic combination therapy is one of the reported effective treatment regimens to combat antimicrobial resistance. Objective: This...
Article in Press
The insufficient documents created challenges for proper use and conservation of medicinal plants in Southwest Ethiopia. Therefore, the present study was aimed to identify and document the medicinal plants, and their ethnopharmacological profiling used by traditional herbalists in Sheka zone. For this, the medicinal plants ethobotanical data was analysed from traditional herbalists (n=23) using qualitative and quantitative...
Article in Press
Herbal plants have long been recognized to possess antimicrobial properties, from ancient medical practice. This study was undertaken to investigate the antibacterial activities of Terminalia ivorensis crude extracts against Staphylococcus aureus and Pseudomonas species isolated from burn wounds. A total of 200 burn wounds swab samples were collected from patients at Alex Ekwueme Federal University Teaching Hospital...
Anti-quorum sensing potential of Ageratum conyzoides L. (Asteraceae) extracts from Burkina Faso.
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Pseudomonas aeruginosa causes infections in human particularly immunocompromised patients with cystic fibrosis, severe burns and HIV, resulting in high morbidity and mortality. The pathogenic bacteria P. aeruginosa produces virulence factors regulated by the mechanism called quorum sensing system. The aim of this study was to assess the anti-quorum sensing activity of Ageratum conyzoides extracts. Chromobacterium violaceum...
Article in Press
This study aims to characterize chemical groups of metabolites in extracts of Acanthospermum hispidum and Croton zambesicus, and to evaluate their anti-inflammatory activities and their immunomodulatory effect on two pro-inflammatory cytokines (TNF? and IL6). The phytochemical screening was done on the powders of both plants by staining and precipitation reactions. Anti-inflammatory activity was performed in vivo on rat...
Article in Press
This study aimed to evaluate the effect of different levels of watercress (Nasturtium officinale) powder on growth performance, antioxidant status, and blood parameters in broiler chickens. A total of 240 day-old male broiler chicks (Cobb-500) were divided into 04 treatments with 04 replicates of 15 birds each. Dietary treatments were included a corn-soybean diet as a control group along with diets containing 0.5, 1 and...
A Mini-review on Musanga cecropioides R. Br. ex Tedlie
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Musanga cecropioides R. Br. ex Tedlie (family Urticaceae) is a tree distributed across some parts of Africa including Nigeria. Ethnomedicinal surveys of Musanga cecropioides implicate that its various parts are used in the management of several health conditions asides the numerous uses reported ethnobotanically. This review was thus aimed at assessing the extent of work done on Musanga cecropioides parts scientifically in...
Article in Press
Several plant extracts inhibit male and female fertility and may be developed into contraceptives. Cassia arereh Del. is a small tree widely spread and used in Nigeria for various purposes. This plant species is employed to restore the fertility among women. This study aimed to investigate the pharmacognostic, phytochemical profiles and the antifertility activity of the leaves of Cassia arereh. The pharmacognostic and...
Ethnobotanical Survey of Medicinal Plants Used in the Management of Asthma in North-Western Nigeria.
Article in Press
: Backgroud: The development of an ethnobotanical research for medicinal plants enables the characterization of botanical knowledge which includes the plants, plants parts used, method of preparation and method of administration of the drug. Variety of plant species from different families are used in the treatment of asthma in north-western part of Nigeria. A collection of these medicinal plants was developed. The...
Article in Press
Folkloric use of Lophira lanceolata in Western Africa for treatment of wounds and some bacterial-associated infections was investigated. In-vitro antibacterial activity against 5 bacterial isolates was done using inhibitory zone diameter (IZD), minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of hydroethanolic extract of Lophira lanceolata (HELL) bark. Ointments of paraffin wax and...
Article in Press
Summary Objectives: To determine the chemical composition and to evaluate the mosquito repellent property of essential oils extracted from the bark of the stem of Sterculia tragacantha Lindl on Anopheles gambiae, vector of malaria. Methods: The essential oil of the stem bark of Sterculia tragacantha Lindl is extracted by hydrodistillation, and their chemical compositions were identified by GC (Ir) and GC-MS. This oil has...
Metabolic profile of wistar rats after consumption of flour prepared with grains and fruits
Article in Press
The occurrence of chronic and degenerative diseases, such as obesity, diabetes, cardiovascular disease (CVD), and cancer is increasing sharply. In the last years, there has been an increase in interest in the consumption of foods with functional properties that are related to weight loss and disease prevention. For these reasons, this study aimed to evaluate the effects of flour prepared with grains and fruits on the...
Article in Press
Introduction: Cognitive decline induced by oxidative brain damage is the critical pathological hallmark of Alzheimer’s disease. Studies have shown that individual administration of Boswellia serrata Roxb (BS), Zingiber officinale Roscoe (ZO) and Ginkgo biloba L. (GB) extracts improved memory and learning through a different mechanism of actions. This study aimed to compare the individual effects of each extract with their...
GC-MS and NMR studies on leaf essential oil of Eucalyptus citriodora from Kaduna, Nigeria
Article in Press
The leaf essential oil of Eucalyptus citriodora Hook belonging to the family Myrtaceae was analysed by GC-MS. The essential oil was obtained by hydrodistillation in yield of 3.5% (v/w). Twenty-nine different components accounting for 100% of the total volatile oils were identified. Citronellal (46.87%) was the predominant monoterpene constituent, followed by isopulegol (7.68%), citronellol (7.47%), 3-tetradecanol (4.98%)...
In-Vivo Anti-Inflammatory activity of different parts of adansonia digitata
Article in Press
The aim of the study is to investigate the anti-inflammatory property of the different parts of Adansonia digitata (Malvaceae) extracts. A. digitata is an important medicinal plant to West Africa including Ghana. The plant is used effectively in folk medicine to treat inflammatory diseases such as joint disorders, asthma, toothache and painful swelling. Carrageenan-induced pedal oedema in 7-day old chicks was used for the...
Pachyrhizus spp. seed extracts control the Sclerotium rolfsii Sacc. mycelial growth
Article in Press
The present paper has aimed to characterize the bioactivity being exerted on S. rolfsii in vitro by seed aqueous extracts from 64 yam bean (Pachyrhizus spp.) genotypes as well as their maceration times (0, 48 and 72 h). Three experiments were carried out following a completely randomized design with 64 treatments (potato-dextrose-agar PDA+extracts) with two controls (PDA with no extract and PDA+Cabrio® Top in the dose of 4...
Article in Press
In the recent past, the importance of freshwater algae has grown enormously due to their antibiotic activity against certain species of bacteria known for several disease states like endocarditis, external otitis, skin rash, etc. Also, there is a growing concern among the immunocompromised individuals that they may be susceptible to antibiotics and anti-fungal resistant infections resulting in increased fatality rates....
Trematocidal activity of certain plant species against rumen fluke Fischoederius cobboldi
Article in Press
The anthelmintic potential of twelve solvent extracts of four plant species were studied against adult Fischoederius cobboldi using in vitro systems. Generally the ethyl acetate extracts of all the plants showed prominent activity by inhibiting the fluke’s motility and reducing their survival in a concentration dependent manner. Compared to the vehicle treated controls, a very significant (P
Paeonia emodi: A threatened important medicinal plant of higher himalayan region
Article in Press
Himalaya is well known for its rich biodiversity with respect to medicinal and aromatic plants and Paeonia emodi Wall. ex Royle is one of them locally known as Chandra (family Paeoniaceae). In India, it is distributed in North–West Himalaya from Kashmir to Garhwal-Kumaun regions of Uttarakhand with an altitudinal range of 1800 to 2800 m asl. P. emodi is highly effective for uterine diseases, blood purifier, colic,...
Extraction and identification of antiviral and antitumor compounds from some marine algae in Egypt
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Marine algae are considered a diverse source of bioactive compounds. This study aimed to detect the presence of antiviral and anticancer potential in extracts of marine algae ,extraction, purification and identification of some marine algae in Egypt were conducted.Water and solvent extraction of Ulvalactuca, Sargassumdentifolium, and Cystoseiaramyrica was conducted. A sequence of extractions, including ethanol (EtOH),...
Article in Press
Due to the action of essential oils of thyme, lemongrass and rosemary against microorganisms and little studies about these essential oils on vegetable seed treatment, the aim of this study was to evaluate the effect of the treatment with these essential oils on cauliflower seeds inoculated with A. flavus and the effect in the physiological and sanitary quality. Cauliflower seeds inoculated with the fungus Aspergillus sp....
Article in Press
Alcohol withdrawal syndrome (AWS) is a common medical problem that can occur as a result of reducing or cessation of alcohol consumption and lead to alcoholic relapse. The objective of the present study is to investigate the neuroprotective effect of an acetone water extract from Moroccan Cistus Monspeliensis (CM) against the development of AWS and its associated disorders. To study AWS related disorders and possible...
Medicinal Plants with Potential to Regulate Male Fertility
Article in Press
The strain on our environment due to increase in population is a major threat to the goals of sustainable development. The need to control population growth for conserving natural resources has led us to explore methods to control population. The best method to control population is to encourage and educate people about various contraceptive methods. There are various methods and technologies that are used to overcome this...
Article in Press
The nutraceutical composition of Sarcodon sp, a wild edible mushroom has outstanding biological activities. However, up to now, not enough nutraceutical information has been reported for this fungus in Mexico, that is, about its preventive and/or therapeutic capacity. The purpose of this work was to describe taxonomically this mushroom and to determine total phenolic contents as equivalents of gallic acid, phenolics acids...
Article in Press
The documentation of medicinal uses of plants is becoming increasingly urgent because of the rapid loss of the natural habitat for some of these plants due to anthropogenic activities. Traditional knowledge of medicinal plants is also at risk of extinction due to the dependency on oral transmission, and as such, there is an urgent need to document such knowledge. The study aimed at document medicinal plants used in the...
Endophytic Aspergillus sp. Isolated from leaves of Mangifera indica, and its Biological activities
Article in Press
Endophytic compounds from Nigerian plants is of significant interest in the search for drug compounds possibly due to their potentials to contribute new compounds with biological properties in the fight against drug resistance pathogens. Consequently, this study was embarked upon to investigate the bioactivities of secondary metabolites of endophytic Aspergillus sp. isolated from the leaves of Mangifera indica. Fresh...
In Vitro Antioxidant and Anti-diabetic Activities of Carica papaya Seed Extracts
Article in Press
Carica papaya seeds have been reported in folklore medicine as a remedy used in treating diabetes mellitus without a proper documented possible mode of action. This study aimed at evaluating antioxidant and anti-diabetic activities of Carica papaya seed extracts in vitro. The air-dried ripe seeds were coarsely powdered and extracted via the soxhlet method to obtain their crude extracts. The crude extracts were then...
Article in Press
Most of the wet land area either remains unutilized or underutilized for cultivation and conservation of economic species. The area either remains covered by means of weeds or unmanaged as such lies useless. The present article introduces a model of ‘Aquatic herbal garden’ developed by Herbal research and development Institute (HRDI) at its camps in Mandal area to utilize such partially or fully waterlogged area to...
Assessment of Active Components from Invasive Alien Plant Species Distributed in Bihar
Article in Press
Plant pathogenic microbes are on rise and thus causing plants quality deterioration. Use of chemicals to lessen their effect, knowingly or unknowingly leaves their side effects. Natural product, a suitable alternative as antimicrobial agent to curb effect of such plant pathogenic microbes has led to study many rare and uncommon plants. Our study aimed to find some active constituents from invading alien species (IAS)...
Article in Press
It was reported in 2005 during WHO survey that about 70-80% of the world population use medicinal plants either in their crude unmodified form or partially in their modified semi-synthetic form of plant sources in their primary healthcare. The present study investigated the phytochemicals and antimicrobial activities of the leaf extracts of Cerathoteca sesamoides and Chromolaena odorata to ascertain their potentials in...
Levels of heavy metals in four malawian medicinal plants used for treatment of infectious diseases
Article in Press
Medicinal plants could potentially be contaminated with heavy metals during growing in the field, processing and/or handling. These heavy metals may be toxic to humans and cause damage to organs such as liver, kidneys and lungs. Currently, there is no data available on the levels of heavy metals in medicinal plants traditionally used for management of infectious diseases in Malawi. The aim of this study was to determine...
Technical feasibility of products based on camu-camu (Myrciaria dubia): a review.
Article in Press
Camu-camu (CC) is a fruit from the Amazon that has been well studied and has great therapeutic potential. The present study was aimed at reviewing botanical, phitochemical and processing aspects of this fruit, in addition this biological effect. Results: Despite the amount of information available regarding this fruit and the potential use of this plant, the market lacks products based on camu-camu. This work summarizes...
Article in Press
Neurodegenerative diseases refer to physiological changes leading to death of nerve cells present in the brain and spinal cord. Current treatment for this disease is not effective and caused many side effects. Thus, the search for alternative medicines is in high demand. Therefore, the aim of this study is to evaluate the anti-cholinesterase properties of Phaleria macrocarpa (leaf). Bioactive compounds from Phaleria...
Insecticidal effect of Hyptis suaveolens chemotype 1,8- cineole on lice, poultry parasites
Article in Press
Aromatic plants can provide potential alternative solutions to synthetic molecular currently used in the control of poultry ectoparasites because they are a rich source of bioactive chemicals. The purpose of this study is therefore to analyze the chemical constituents of the essential oil of H. suaveolens and to evaluate the insecticidal effect on lice parasite in chicken and turkey. A gas chromatographic analysis...
Article in Press
Diabetes affects 422 million people in the world and caused 1.5 million deaths. The Psydrax genus has been reported to have various pharmacological activities. Based on ethno-pharmacological information, Psydrax horizontalis Schum. & Thonn. (Bridson) locally known as “Akata-ike†in Nsukka is used in the management of diabetes in South-eastern Nigeria. However, as at the time of this research, no previous work has been...
Article in Press
Traditional medicine is used in all over the world, especially in developing countries. Though synthetic drugs are very effective but are harmful to human beings because of their side effects. Genus of Terminalia and Combretum species are belong to the family Combretaceae, which contains 20 genera and 600 species as herbs, shrubs and trees. These plants are used in different traditional medicine for their antioxidant...
Article in Press
In Ethiopia, many plants are used for medicinal purpose by traditional healers without any scientific justification for their therapeutic values. The principal Aim of this study were to evaluate the in vitro antibacterial and antifungal activities of the leaf, root and stem bark extracts of Rhamnus prinioides (gesho), Justicia schimperiana (sensel) and Ruta chalepensis (Tena adam) against some common pathogenic species of...
Article in Press
The concentrations of essential macro and micro elements were determined using Energy Dispersive X-ray Fluorescence technique (EDXRF) being the most suitable instrument for the multi-element analysis in plant samples. Two macroelements (Ca and K) and seven microelements (Fe, Mn, Zn, Cu, Rb, Sr and Br) were analyzed in different parts (leaves, wood bark and roots) of Durio zibethinus Murr. The results revealed the levels of...
Article in Press
Reports from extensive surveys have indicated that about 70-80% of the world population; particularly in the developing countries rely on non-conventional medicine mainly of herbal origins for their primary health care. Correct identification and quality assurance of the starting materials are essential prerequisites to ensuring reproducible quality of herbal medicine which will contribute to its safety and efficacy. This...
Article in Press
Plant part such asleaves, stems, branches, twigs, and roots possess different therapeutic functions and activities. Besides that, development stages, either young or mature could cause several effects to the bioactive compounds as well as the antioxidant properties of the plant. Thus, an experiment was conducted using a nested design, with three replications, involved young and mature development stages and three different...
ETHNOMEDICINAL EVALUATION OF SOME ANTIMALARIAL PLANTS USED IN ONDO STATE, NIGERIA
Article in Press
The use of herbs and plant materials have always been popular in the treatment of febrile illness, and it has grown over time in malaria endemic areas. Structured questionnaires were administered in four towns in each of the three senatorial districts of Ondo state to know the most commonly used herbs and the results suggested Mango (Mangifera indica) Siam weed (Chromolaena odorata) and Guava (Psidium guajava) as most...
Article in Press
Antifungal activity of the ethanolic extract of Alchornea cordifolia plant was evaluated both in vitro and in vivo against Aspergillus fumigatus, and Aspergillus terreus, mostly implicated in plant and animal fungal diseases. Antifungal potential of the extract were evaluated quantitatively in vitro using well diffusion method and in vivo by studying the survival rate of Drosophila melanogaster (Harwich) challenged with...
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