March 2017

Pharmacological potential of Palicourea rigida kunth: A possible participation of flavonoid compounds

Palicourea rigida Kunth (Rubiaceae), also called “bate-caixa” or “douradão”, has been used as antihypertensive, antiulcerogenic, anti-inflammatory and analgesic by traditional communities. Pharmacological potential of the ethanol extract from P. rigida (EEPR) and two quercetin derivatives were investigated. Using the high performance liquid chromatography (HPLC) assay, EEPR was analyzed....

Author(s): Muiara Aparecida Moraes, Bruna Celeida Silva Santos, Rodrigo Luiz Fabri, Elita Scio, Maria Silvana Alves, Célia Hitomi Yamamoto, Mírian Pereira Rodarte, Glauciemar Del-Vechio-Vieira, Ana Lúcia dos Santos de Matos Araújo, Aílson da Luz André de Araújo and Orlando Vieira de Sousa

March 2017

In vitro cytotoxic potential of Yacon (Smallanthus sonchifolius) against HT-29, MCF-7 and HDFn cell lines

Yacon (Smallanthus sonchifolius) tubers and leaves have been used widely as foodstuff and as remedy for urinary ailments, muscle pain, hyperlipidemia and diabetes mellitus. Recent studies have investigated on isolating active components for their anti-cancer potential against melanoma, cervical cancer and colon cancer.  In this study, the cytotoxicity potential of hexane, methanol and DCM extracts of yacon leaves...

Author(s): Rachelle P. Mendoza, Warren S. Vidar and Glenn G. Oyong