May 2014

Detection of tamarixetin and kaempferide in different tissues by high-performance liquid chromatography in tamarixetin and kaempferide treated rats

Tamarixetin and kaempferide were considered as the major active constituents of Tamarix chinensis, and had several known bioactivities. An effective and inexpensive high-performance liquid chromatographic method was established and validated for the determination of tamarixetin and kaempferide in rat tissues following a single oral administration. Tissue distribution showed the highest level of tamarixetin was observed...

Author(s): Fu-quan Xu, Yuan-yuan Feng and Bin-lun Yan

May 2014

Development of phytochemical fingerprint of an Indian medicinal plant Chitrak (Plumbago zeylanica L) using high performance thin layer chromatography (HPTLC)

Fresh, shade-dried and powdered samples of leaf, stem and root of Chitrak (Plumbago zeylanica L) were subjected to fractional distillation in a Soxhlet apparatus using four organic solvents. Chloroform, acetone and ethanol extracts from root of Plumbago showed higher zone of inhibition of 22.66±1.52, 21.5±1.29 and 16.5±1.29 mm and minimum inhibitory concentration (MIC) of 1.0, 10.0 and 10.0...

Author(s): I. C. Mohanty, Vishnu K. Soni and G. R. Sahu

May 2014

Antibacterial activity of two triterpenes from stem bark of Protorhus longifolia

Antibiotic resistance of pathogenic strains has hugely contributed to the wide spread of new and re-emerging infectious diseases. There is thus the need for the discovery of new (non-penicillin based) antibiotics. The triterpenes [3β-hydroxylanosta-9,24-dien-21-oic acid (1) and methyl-3β-hydroxylanosta-9,24-dienoate (2)] isolated from stem bark of Protorhus longifolia (Benrh.) Engl. were evaluated for their...

Author(s): Rebamang A. Mosa, Mandlakayise L. Nhleko, Thandeka V. Dladla and Andy R. Opoku