September 2016

Antifungal activities of crude extracts of some Nigerian chewing sticks

Preliminary screening of both methanol and aqueous extracts of the stem and root of Distemonanthus benthmianus, Treculia africana, Garcinia kola and Anogessus leiocarpus was carried out to test for antifungal activity. This was investigated using disc diffusion technique by measuring the zone of inhibition of the fungi after infusion with the plant extract. This produced definite antifungal activity against the...

Author(s): T. S. Ewekeye, O. A. Oke and A. G. Emoh

September 2016

Antimicrobial effect of chalepensin against Streptococcus mutans

Dental diseases play an important role in public health. The use of conventional antibiotics for treatment can create microbial resistance; therefore, it is critical to search for alternatives to which there is no such an effect. In this regard, we have studied the in vitro effect of chalepensin, from the plant Ruta chalepensis L., against the dental caries etiological agent Streptococcus mutans. R. chalepensis is...

Author(s): Ricardo Gomez-Flores, Marcela Alejandra Gloria-Garza, Myriam Angélica de la Garza-Ramos, Ramiro Quintanilla-Licea and Patricia Tamez-Guerra

September 2016

Antitumor activity of Pachycereus marginatus (DC.) Britton & Rose extracts against murine lymphoma L5178Y-R and skin melanoma B16F10 cells

Pachycereus marginatus (DC.) Britton & Rose is a species belonging to the family Cactaceae. In traditional medicine, it is recommended to treat diabetes and gastrointestinal infections; however, there are no studies related to its use in cancer treatment. The in vitro antitumor effect of P. marginatus hexane, chloroform, methanol, and methanol-aqueous partition stem extracts, against murine lymphoma L5178Y-R and...

Author(s): Humberto Carlos Hernández-Martínez, Ricardo Gomez-Flores, Patricia Tamez-Guerra, Ramiro Quintanilla-Licea, Mario Ángel Samaniego Escamilla, Enriqueta Monreal-Cuevas, Reyes Tamez-Guerra and Cristina Rodriguez-Padilla