July 2016

The impact of compounds isolated from Ocimum sp. on apoptotic activity of osteoclast

Periodontal disease has multifactorial etiology. The immune response to the microbial challenge leads to osteoclast activation and resorption of the alveolar bone, resulting in tooth loss. Compounds isolated from Ocimum americanum and Ocimum basilicum were analyzed for apoptotic activity towards osteoclast in this study. Steam distillation was used for the extraction of essential oils (EOs) from dry leaves and flowers....

Author(s): Paulo J. L. Juiz , Roberto Gambari, Roberta Piva, Letizia Penolazzi, Franceli Silva, Reinaldo J. C. Alves, Angélica M. Lucchese and Ana Paula T. Uetanabaro

July 2016

The effects of an aqueous leaf extract of Clausena anisata (Willd.) Hook.f.ex Benth. on blood pressure, urine output, angiotensin II levels and cardiac parameters in spontaneously hypertensive rats

Clausena anisata (Willd.) Hook.f. ex Benth (Rutaceae) is a medicinal plant indigenous to Southern Africa and scientific studies report on its biomedical activities and possible antihypertensive property by demonstrating in vitro angiotensin converting enzyme  inhibition. This study investigated the antihypertensive effects of an aqueous leaf extract of Clausena anisata in a spontaneously hypertensive rat model, and...

Author(s): Ntamo MacDonald Tshepo Lechaba, Paul Jacobus Schutte, Leon Hay, Linde Böhmer and Melvin Megandran Govender