May 2021

In vivo study of antiplasmodium and histological activity of Garcinia kola and Aloe vera extracts against falciparum malaria

This study focuses on testing the efficacy of herbal remedy used in many homes within the South-Eastern part of Nigeria to treat malaria and also the histopathological effect of the remedy on albino rats. Twenty rats were procured and distributed with five rats to one group. Group 1 received Garcinia kola and Aloe vera extracts, Group 2 received only G. kola extract, Group 3 is negative control and Group 4 is positive...

Author(s): Onyinyechi Cecilia Amobi-Alor, Adanna Cynthia Eze, Chineye Lucy Ugwute, Nneka Mariam Unachukwu, Chika Udeh, Simeon Okolo, Chidimma Claribel Chikezie, Kelechi Mbah-Omeje and Felix Chukwuebuka Onyia  

May 2021

New naphthalene derivative isolated from Diaporthe sp. host to Syzygium cordatum Hochst.ex Krauss plant

Fungal endophytes are regarded as inexhaustible sources of pharmaceuticals and agrochemicals with profound antibacterial, anticancer or antifungal activities. Diaporthe sp., an endophytic fungus residing in medicinal plant S. cordatum, showed a good antagonism against bacterial pathogens of beans; Pseudomonas syringae pv phaseolicola (Psp) and Xanthomonas axonopodis pv phaseoli (Xap), with zones of inhibitions of 14.00...

Author(s): Towett Kipngetich Erick, Joyce Jepkorir Kiplimo and Josphat Matasyoh  

May 2021

Berberis vulgaris aqueous extract prevention of carbon tetrachloride induced hepatotoxicity and lipopolysaccharides/paracetamol induced hepatitis in rats

The aim of this study was to evaluate the effect of Berberis vulgaris water extract (BWE) against CCl4-induced hepatotoxicity and LPS/PCM induced- hepatic inflammation in the experimental animal models. CCl4 (100 ug/kg, oral) administration for 28 days as well as the co-administration of LPS (250 ug/kg bw) and PCM (2 g/kg bw) for 28 days resulted in massive elevation in serum and hepatic prooxidants and inflammatory...

Author(s): Mohamed Ahmed Moustafa, Doaa Ahmed Ghareeb, Maha A. El-Demellawy, and Mohamed Mahmoud Elsayed  

May 2021

Bioactive profile of mandacaru fruits and cytotoxicity against the L929 cell line

Mandacaru (Cereus jamacaru DC. Subsp. Jamacaru) is native to the Brazilian Caatinga and is part of the Cactaceae family. Mandacaru fruits are attractive in taste and flavour, although they are not widely commercialised. However, there is limited scientific literature on the composition of this fruit. Therefore, the present work was aimed at analysing the physicochemical composition, as well as in vitro antioxidant...

Author(s): Jamiles Francisca dos Santos, Jenisson Linike Costa Gonçalves, Raphael Amancio de Jesus, Paulo Cesar de Lima Nogueira, Ricardo Scher, Antonio Martins de Oliveira Júnior and Jane de Jesus da Silveira Moreira,  

May 2021

Polyphenols quantification and antioxidant activity of methanolic and aqueous extracts from eight medicinal plants used to manage avian diseases in Burkina Faso

The present study aimed to quantify the polyphenols and evaluate the antioxidant activity of methanolic and aqueous extracts from eight medicinal plants used by the poultry farmers to manage avian diseases in Burkina Faso. Total phenolics and total flavonoids were quantified using Folin-Ciocalteu and AlCl3 reagents, respectively. The antioxidant activity was evaluated using three methods:...

Author(s): Windmi Kagambega, Roland Nâg-Tiéro Meda,Benjamin Kouliga Koama ,, Anne-Flora Drabo, Hadidjatou Belem, Der Dabire, Jacques Kabore, Amadou Traore and  George Anicet Ouédraogo