November 2007

Cell protective antioxidants from the root bark of Lannea velutina A. Rich., a Malian medicinal plant

Antioxidants (radical scavengers and 15-lipoxygenase inhibitors) in semipolar extracts of root bark from the Malian medicinal plant Lannea velutina have been investigated. A series of proanthocyanidins with degree of polymerization from 2 to more than 12 have been isolated, in addition to the monomeric substance, catechin. The major constituents have a degree of...

Author(s): Ababacar Maiga, Karl Egil Malterud, Gro H. Mathisen, Ragnhild E. Paulsen, Jane Thomas-Oates, Ed Bergström, Leon Reubsaet, Drissa Diallo and Berit Smestad Paulsen    

November 2007

Protective effect of Picrorhiza kurroa on antioxidant defense status in adriamycin-induced cardiomyopathy in rats

Adriamycin, an anthracycline antibiotic, which is used in the treatment of various tumors, is known to cause severe cardiomyopathy. The present study examined the protective effects of Picrorhiza kurroa, an ayurvedic medicinal plant, on myocardial antioxidant defense system in adriamycin-induced cardiomyopathy in rats. Intraperitoneal administration of adriamycin (1.5 mg/kg body weight/ day, i.p. for 15 days)...

Author(s): D. Rajaprabhu, R. Rajesh, R. Jeyakumar, S. Buddhan, B. Ganesan, and R. Anandan    

November 2007

Evaluation of red and white seed extracts of Abrus precatorius Linn. against freund’s complete adjuvant induced arthritis in rats.

Abrus precatorius (Fam: Leguminosae) is a folklore medicinal plant traditionally indicated to treat cancer, ulcer and fever. The purpose of the present study was aimed to evaluate the comparative therapeutic potential of both A. precatorius white (APW) and A. precatoriusRed (APR) seed extracts on Freund’s complete adjuvant induced arthritis in rats. The investigated result showed that the APW (250...

Author(s): M. Sudaroli and T. K. Chatterjee