October 2019

Hypoglycemic activity of Antidesma bunius (L.) Spreng and Mollugo oppositifolia L. fresh and alcoholic extracts in the db/db diabetic mouse model

Antidesma bunius (L.) Spreng and Mollugo oppositifolia L., also known as “bignay” and “malagoso” respectively, are commonly used medicinal plants in the Philippines to treat diabetes. However, the hypoglycemic effect of A. bunius (L.) Spreng and M. oppositifolia L. has not been reported to date. Therefore, this study was undertaken to investigate the hypoglycemic effects of the fresh and...

Author(s): N. C. Tanquilut, N. Q. Alonzo, A. E. James, D. K. Rowlands, G. C. Sanchez, R. D. San Jose, E. Yesner, M. R. C. Tanquilut and B. A. S. Reyes,  

October 2019

Chromatography and bioautography of endophytic fungi extracts of Uncaria tomentosa (Willd.) DC with antibacterial activity

Endophytic fungi of different species have already proved their efficacy against a range of pathogenic bacteria. However, the separation of the compounds contained in these extracts that actually have an effective activity is not a constant, but it is essential for the scientific knowledge to formulate a new medication. Thus, this study aimed to separate compounds from two endophytic fungi extracts of Uncaria tomentosa...

Author(s): Fernando Generoso da Silva GONÇALVES, Jonatas Conceição de ARAÚJO, Dionízio da Silva BRASIL, Rodrigo Asfury RODRIGUES and Clarice Maia CARVALHO  

October 2019

Antifungal efficacy of crude extracts of Azadirachta indica and Vernonia amygdalina against pathogenic Aspergillus niger (ATCC 16404)

This research work was conducted to assess the potency of ethanolic and hot water extract of Azadirachta indica and Vernonia amygdalina against pathogenic Aspergillus niger (ATCC 16404). Potato Dextrose Agar was the medium under which the antimicrobial sensitivity test was carried out. Streptomycin solution was also added to the medium to selectively inhibit the growth of bacterial cell. The results showed that, higher...

Author(s): Ninkuu V., Adetunde, L. A., Sackey I., Opoku N. and Diedong P.  

October 2019

Biotechnological potential of the Carapa guianensis, Bertholletia excelsa and Copaifera spp. oils

The use of vegetable species for treatment or prevention of diseases is one of the most ancient medicine techniques in humanity. In Amazon rainforest, there are numerous of plant species that possess biotechnological potential, and due to this, this study aimed at carrying out a bibliographic review describing the biotechnological potential in Carapa guianensis, Bertholletia excels, and Copaifera spp. oils. This study...

Author(s): Naila Fernanda Sbsczk Pereira Meneguetti, Dionatas Ulises de Oliveira Meneguetti,, and Amauri Siviero,  

October 2019

Evaluation of hepatoprotective, antioxidant and cytotoxic properties of aqueous extract of turmeric rhizome (Turmesac®)

In the present study, the hepatoprotective, antioxidant and cytotoxic activities of aqueous extract of turmeric rhizome (Turmesac®) were evaluated. In brief, Turmesac® was extracted from turmeric rhizome. 3-(4,5- dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) assay was used to evaluate the hepatoprotective and cytotoxic activities of the Turmesac® against the human liver (HUH-7) and breast cancer...

Author(s): C. T. Sadashiva, H. M. Firoz Hussain and S. Nanjundaiah