September 2007

Acute effect of administration of ethanol extracts of Ficus exasperata vahl on kidney function in albino rats

Administration of ethanol extracts Ficus exasperata. Vahl at doses 50, 200, 500 mg/kg body weight resulted in body weight gain in all extract -administered groups over a 3-day period. Mean relative kidney weight increased from 7.5 x 10-3 ± 8.7 x 10-4 in the control group to 1.2 x 10-2 ± 5.3 x 10-5 in the highest dose group. Serum urea concentration also increased in a dose...

Author(s): Ijeh Ifeoma Irene and Ukweni Ajike Iheanacho      

September 2007

Biochemical and toxicological studies of aqueous extract of Tithonia diversifolia (Hemsl.) leaves in wister albino rats.

The effects of aqueous extracts of Tithonia diversifolia leaves on some biochemical indices such as body weight, blood parameters and liver functions were investigated in albino male wister rats. The safe dosage of the aqueous extract of T. diversifolia leaves were daily injected intraperitoneally (P≤0.05) to a group of Wister strain rats over a period of 7 and 14 days respectively. During these...

Author(s): Oyewole, I. O., Magaji, Z. J. and Awoyinka, O. A.    

September 2007

Effects of aqueous extract of Ganoderma lucidum on blood glucose levels of normoglycemic and alloxan-induced diabetic wistar rats

Ganoderma lucidum mushroom has long been used as a potent medicinal plant in the far East, but its ethnomedicinal importance in Nigeria is yet to be fully realized. The effects of the aqueous extract on blood glucose levels of alloxan induced and normal Wistar rats have been investigated. Three doses of the extract (250, 500 and 1000 mg/Kg) were administered intraperitoneally. The dose of 250 mg/Kg of the extract...

Author(s): A. Mohammed, A. B. Adelaiye ,M. S. Abubakar and E. M. Abdurahman      

September 2007

Effect of Central/South American medicinal plants on energy harvesting ability of the mammalian GI tract

Diabetes mellitus (DM) and associated co-morbidities including cardiovascular disease (CVD) and obesity (OB) are fast becoming leading causes of mortality in the developed and developing world. While the etiologies of these diseases are not completely understood, they are often associated with excessive caloric intake, hyperglycemia, irregular blood lipid levels and resulting oxidative stress. One important strategy for...

Author(s): Huerta, V., Mihalik, K., Maitin, V. Crixell, S. H. and Vattem, D. A.