Journal of
Physiology and Pathophysiology

  • Abbreviation: J. Physiol. Pathophysiol.
  • Language: English
  • ISSN: 2141-260X
  • DOI: 10.5897/JPAP
  • Start Year: 2010
  • Published Articles: 52

Table of Content: July-December 2021 ; 12(1)

July 2021

Antifertility effects of crude extracts from Acacia nilotica pods and Albizia lebbeck stem bark in female multimammate rats, Mastomys natalensis

The study's main objective was to assess any pathophysiological significance of Acacia nilotica pods aqueous extract and Albizia lebbeck stem bark methanolic extract on the reproductive system of female multimammate rats (Mastomys natalensis). A total of 60 sexually mature female rats were randomized into a 2 × 3 factorial experimental design for treatments (Control, A. nilotica, and A. lebbeck) and treatment...

Author(s): Lusekelo M. Mwangengwa, Gaymary G. Bakari, Noel L. Kanuya and Robert A. Max

August 2021

Assessment of endothelial function in subjects with obstructive sleep apnea hypopnea syndrome

Obstructive sleep apnea hypopnea syndrome (OSAHS) is characterized by recurrent episodes of interruption of ventilation responsible for hypoxemia, hypercapnia and hyper activation of the autonomic nervous system. Hypoxemia followed by re-oxygenation promotes the formation of free radicals, oxidative stress and vascular inflammation, leading to endothelial dysfunction. The objective of this cross-sectional study...

Author(s): Fatoumata Bâ, Fatou Bintou Sar and Abdoulaye Bâ

August 2021

Intentional mismatch in primer design to stabilize discrimination of CFTR and adenovirus targets

The purpose of this study was to apply an intentional mismatch design technique for primer-based detection of gene targets. In this study, wild-type versus mutant cystic fibrosis transmembrane conductance regulator alleles as well as two related adenovirus B7 and E4 genomes were used to test discrimination of primers. Lambda viral DNA genome template as well as published primers versus purified human genome template was...

Author(s): Emma L. Bush, Katelyn D. Johnson, Akhil Sekar, Kate Gislason, Caleb W. Furlow, Michael J. Reiterman and Douglas B. Luckie