Journal of
Physiology and Pathophysiology

  • Abbreviation: J. Physiol. Pathophysiol.
  • Language: English
  • ISSN: 2141-260X
  • DOI: 10.5897/JPAP
  • Start Year: 2010
  • Published Articles: 45

Table of Content: May 2019; 10(1)

May 2019

Carpolobia lutea methanol root extract reinstates androgenesis and testicular function in cadmium-challenged rats

Cadmium produces a wide range of biological dysfunctions in human and laboratory animals where it chiefly affects the testes, whereas, Carpolobia lutea has been known to have antioxidant benefits. This study was intended to investigate the effects of Carpolobia lutea root extracts on testicular hormone function in cadmium-challenged male rats. 48 male Wistar rats (170-190 g) were divided into six groups, each containing...

Author(s): Ejike Daniel Eze, Okpa Precious Nwaka, Igbokwe Ugochukwu Vincent, Moses Dele Adams, Karimah Mohammed Rabiu and Ayikobua Emmanuel Tiyo  

May 2019

Evaluation of the cytoprotective effects of anti-ulcer agents in acid-alcohol induced gastric ulceration in wistar rats

Adequate studies have been done using proton pump inhibitors and H2-receptor antagonist and only few studies for cyto-protective and gastric acid secretions have been done in Nigeria. Therefore this work studied the cyto-protective and gastric acid secretory effects of rabeprazole, ranitidine, omeprazole and cimetidine in wistar rats. 28 male wistar rats of weights 300 to 400 g were recruited and randomly divided into...

Author(s): Nworgu Choice, Celestine Ani, Ugwuishi Emeka, Okorie Pamela, Anyaeji Pamela, Ugwu Princewill, Uzoigwe Jide, Igwe Uzoma and Nwachukwu Daniel