Medical Case Studies

  • Abbreviation: Med. Case Stud.
  • Language: English
  • ISSN: 2141-6532
  • DOI: 10.5897/MCS
  • Start Year: 2010
  • Published Articles: 40

Short Communication

Primary non Hodgkin’s lymphoma of the orbit: A case report

Essadi I
  • Essadi I
  • Department of Medical Oncology, Military Hospital MOHAMMED V, Rabat, Morocco.
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Tazi EM
  • Tazi EM
  • Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
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Allam W
  • Allam W
  • Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
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W, Sbitti
  • W, Sbitti
  • Department of Medical Oncology, Military Hospital MOHAMMED V, Rabat, Morocco.
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Y, Ichou M
  • Y, Ichou M
  • Department of Medical Oncology, Military Hospital MOHAMMED V, Rabat, Morocco.
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Errihani H
  • Errihani H
  • Department of Medical Oncology, National Institute of Oncology, Rabat, Morocco.
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  • Article Number - 7A473D0510
  • Vol.2(2), pp. 19-21, February 2011
  •  Accepted: 29 December 2010
  •  Published: 28 February 2011

Abstract

 

Lymphoma is the most common malignancy of the orbit and the eyelids, accounting for 10% of malignant orbital tumors in adults. Orbital lymphomas can arise primarily in the orbit or represent a manifestation of disseminated disease. In this paper we report a case of early stage orbital lymphoma, which was managed successfully with chemotherapy, and a review of the related literature. A Moroccan Muslim woman aged 76 years, who presented a left orbital swelling. Ophthalmological examination complemented by CT has objectified orbital mass, whose biopsy was in favour of a non Hodgkin's lymphoma (NHL) large cell B. The patient was classified as stage IE after a record expansion. She was managed successfully with 6 courses of Rituximab 375 mg/m², Cyclophosphamide 750 mg/m² d1, Doxorubicine 50 mg/m² d1, Vincristine 1.4 mg/m² d1, and prednisone 50 mg/m² d1-5 (R-CHOP) regimen, with complete response. This case highlights the important role of R-CHOP regimen for achieving successful treatment cure for patients having an early stage orbital lymphoma

 

Key words: Orbit, non hodgkin’s lymphoma, large cell, chemotherapy