February 2011

Evaluation of essential oils composition of methanolic Allium sativum extract on Trypanosoma brucei infected rats

  The essential oils composition and anti – trypanosomal activity of fermented methanolic Allium sativum extract was investigated. The crude extract was partially purified using column chromatography to give fractions A, B and C, which were further characterized by gas chromatographic – mass spectral (GC/MS) analysis. The fractions identified thirteen, sixteen and seventeen compounds...

Author(s): Oluwatosin K. Yusuf and Clement O. Bewaji

February 2011

Effect of EDTA on the activity of ciprofloxacin against Shigella sonnei

Ethylenediamine Tetraacetic Acid (EDTA) is a compound predominantly known for its chelating ability. It has also been found that in combination with antibacterial agents like benzakolium and chlorocresol, they were able to kill resistant bacteria. EDTA was used in combination with ciprofloxacin, a fluoroquinolone, against Shigella sonnei. This was done by determining their respective and combined Minimum Inhibitory...

Author(s): Clement Jackson, Musiliu Adedokun, Emmanuel Etim, Ayo Agboke, Idongesit Jackson and Emmanuel Ibezim