February 2011
Evaluation of essential oils composition of methanolic Allium sativum extract on Trypanosoma brucei infected rats
The essential oils composition and anti – trypanosomal activity of fermented methanolic Allium sativum extract was investigated. The crude extract was partially purified using column chromatography to give fractions A, B and C, which were further characterized by gas chromatographic – mass spectral (GC/MS) analysis. The fractions identified thirteen, sixteen and seventeen compounds...
February 2011
Effect of EDTA on the activity of ciprofloxacin against Shigella sonnei
Ethylenediamine Tetraacetic Acid (EDTA) is a compound predominantly known for its chelating ability. It has also been found that in combination with antibacterial agents like benzakolium and chlorocresol, they were able to kill resistant bacteria. EDTA was used in combination with ciprofloxacin, a fluoroquinolone, against Shigella sonnei. This was done by determining their respective and combined Minimum Inhibitory...
