The essential oils composition and anti – trypanosomal activity of fermented methanolic Allium sativum extract was investigated. The crude extract was partially purified using column chromatography to give fractions A, B and C, which were further characterized by gas chromatographic – mass spectral (GC/MS) analysis. The fractions identified thirteen, sixteen and seventeen compounds respectively. The main components were oxygenated hydrocarbon (palmitoleic and steric acid) and n – hydrocarbon (unsaturated). The crude extract show anti- trypanosomal activity on Trypanosoma brucei infected rats.
Key words: Allium sativum, essential oils, gas chromatographic – mass spectral analysis, retention index (KI, anti- trypanosomal).
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