July 2011
Qualitative (phytochemical) analysis and antifungal activity of Pentas decora (De wild), a plant used traditionally to treat skin fungal infections in Western Uganda
The ethanolic leaf extract of Pentas decora, a plant known in the local community as “Kabyakyasha” (in Runyankole Language), was evaluated for its antifungal activity against Candida albicans,Epidermophyton floccosum, Microsporum canis and Trichophyton rubrum, and qualitatively analyzed for its phytochemical composition. The disc diffusion method was employed to...
July 2011
Phytochemical and biological study of Striga hermonthica (Del.) Benth callus and intact plant
Preliminary phytochemical screening of Striga hermonthica was carried out to assess the chemical contents and biological activity of callus comparing to that of intact plant (upper and underground parts). The results show the presence of terpenes, tannins, coumarins, cardiac glycosides, flavonoids, saponins, anthracenosides and alkaloids. Further, ethanol extracts analysis-using thin layer...
July 2011
Assessment of radiation-induced DNA damage by comet assay in cultured HeLa cells treated with guduchi (Tinospora cordifolia Miers) before exposure to different doses of g-radiation
The radiomodulatory effect of guduchi extract (TCE) was studied in HeLa cells incubated with 0, 1, 2, 4, 6 or 8 µg/ml of TCE for 2 or 4 h before exposure to 0, 0.5, 1, 2, 3 or 4 Gy of g-radiation. The molecular DNA damage was assessed using alkaline comet assay, where DNA tail fragmentation olive tail moment (OTM) served as a measure of DNA damage. Exposure of HeLa...
