Research in Pharmaceutical Biotechnology

  • Abbreviation: Res. Pharm. Biotech.
  • Language: English
  • ISSN: 2141-2324
  • DOI: 10.5897/RPB
  • Start Year: 2009
  • Published Articles: 43

Table of Content: July 2011; 3(7)

July 2011

Qualitative (phytochemical) analysis and antifungal activity of Pentas decora (De wild), a plant used traditionally to treat skin fungal infections in Western Uganda

  The ethanolic leaf extract of Pentas decora, a plant known in the local community as “Kabyakyasha” (in Runyankole Language), was evaluated for its antifungal activity against Candida albicans,Epidermophyton floccosum, Microsporum canis and Trichophyton rubrum, and qualitatively analyzed for its phytochemical composition. The disc diffusion method was employed to...

Author(s): Taddeo Ahumuza and Claude Kirimuhuzya

July 2011

Phytochemical and biological study of Striga hermonthica (Del.) Benth callus and intact plant

  Preliminary phytochemical screening of Striga hermonthica was carried out to assess the chemical contents and biological activity of callus comparing to that of intact plant (upper and underground parts). The results show the presence of terpenes, tannins, coumarins, cardiac glycosides, flavonoids, saponins, anthracenosides and alkaloids. Further, ethanol extracts analysis-using thin layer...

Author(s): Faisal Hammad Mekky Koua, Hind Ahmed Babiker, Asim Halfawi, Rabie Osman Ibrahim, Fatima Misbah Abbas, Eisa Ibrahim Elgaali and Mutasim Mohamed Khlafallah

July 2011

Assessment of radiation-induced DNA damage by comet assay in cultured HeLa cells treated with guduchi (Tinospora cordifolia Miers) before exposure to different doses of g-radiation

  The radiomodulatory effect of guduchi extract (TCE) was studied in HeLa cells incubated with 0, 1, 2, 4, 6 or 8 µg/ml of TCE for 2 or 4 h before exposure to 0, 0.5, 1, 2, 3 or 4 Gy of g-radiation. The molecular DNA damage was assessed using alkaline comet assay, where DNA tail fragmentation olive tail moment (OTM) served as a measure of DNA damage. Exposure of HeLa...

Author(s): G. C. Jagetia and S. K. Rao