African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Evaluation of antibacterial activity and phytochemical analysis of root extracts of Boscia angustifolia

Hassan, S. W.1*, Umar, R. A.1, Lawal, M.1, Bilbis, L. S.1,  Muhammad, B. Y.2and Dabai, Y. U.3
1Department of Biochemistry, Usmanu Danfodiyo University, P.M.B. 2346, Sokoto, Nigeria. 2Department of Pharmacology, Usmanu Danfodiyo University, P.M.B. 2346, Sokoto, Nigeria. 3Department of Biological sciences, Microbiology unit, Usmanu Danfodiyo University, P.M.B. 2346, Sokoto, Nigeria.
Email: [email protected]

  •  Accepted: 21 July 2006
  •  Published: 18 September 2006

Abstract

The aqueous and organic solvents extracts of Boscia angustifolia were screened for antibacterial and phytochemical properties. Alkaloids and saponins were detected in aqueous and chloroform extracts. These extract fractions were significantly (p<0.05) active against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Streptococcus pneumoniae but did not show activity against Salmonella typhi at concentrations ranging from 10 to 120 mg/ml. The hexane and petroleum ether extracts did not show activity on the bacterial organisms used. All the activities were compared with a standard drug, tetracycline. The Minimum Inhibitory Concentration (M.I.C.) of the aqueous and chloroform extracts was 20 and 10 mg/ml respectively. The results lend scientific credence to justify the use of this plant against some bacterial diseases.

 

Key words: Boscia angustifolia, antibacterial, in vitro screening