May 2014

Efficacy of glucocorticoids in controlling leishmania major infecting Balb/c mice

Leishmaniasis is a growing health problem in many parts of the world. Efforts to find new chemotherapeutics for leishmaniasis remain a priority. This study was carried out to determine the effect of using glucocorticoid drugs to reduce production of chemokine production in a bid to control Leishmania major infection in BALB/c mice. A total of 48 mice were used. In the therapeutic arm (post-infection), 24 mice were...

Author(s): Rose M. Nyamao, Zipporah O. Lagat, Khayeka W. Christopher, Bernard N. Jumba and Rebecca W. Waihenya, Robert Karanja and Bernard Osero Ong&#;ondo