Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3834

Full Length Research Paper

Composition and antifungal activity against Candida albicans, Candida parapsilosis, Candida krusei and Cryptococcus neoformans of essential oils from leaves of Piper and Peperomia species

Andreia de Araujo Morandim-Giannetti1, 2*, Aline Ringis Pin1, Natalia Ama Santo Pietro1, Haroldo Cesar de Oliveira2, Maria Jose Soares Mendes-Giannini2, Alberto Camilo Alecio3, 5, Massuo Jorge Kato4, Jose Eduardo de Oliveira3 and Maysa Furlan3
1Departamento de Engenharia Química, Centro Universitário da FEI, Av. Humberto de Alencar Castelo Branco, 3972, 09850-901, São Bernardo do Campo-SP, Brazil. 2Departamento de Análises Clínicas, Faculdade de Ciências Farmacêuticas, Universidade Estadual Paulista, Rua Expedicionários do Brasil, 1621, 14801-902, Araraquara-SP, Brazil. 3Instituto de Química, Universidade Estadual Paulista, CP 355, 14800-900, Araraquara-SP, Brazil. 4Instituto de Química, Universidade de São Paulo, CP 26077, 05599-970, São Paulo-SP, Brazil. 5Universidade Paulista, Av. Alberto Benassi, 200, 14804-300, Araraquara-SP, Brazil.
Email: [email protected]

  •  Accepted: 02 August 2010
  •  Published: 04 September 2010

Abstract

This study was addressed to investigate the composition and antifungal activity of essential oils from leaves of Piperaceae species (Piper aduncum, P. amalago, P.cernuum, P. diospyrifolium, P. crassinervium, P. gaudichaudianum, P. solmsianum,P. regnellii, P. tuberculatum, P. umbelata and Peperomia obtusifolia) againstCandida albicans, C. parapsilosis, C. krusei and Cryptococcus neoformans. The essential oils from P. aduncum, P. gaudichaudianum and P. solmsianum showed the highest antifungal activity against Cryptococcus neoformans with the MIC of 62.5, 62.5 and 3.9 mg.mL-1, respectively. The oil from P. gaudichaudianum showed activity against C. krusei with MIC of 31.25 mg.mL-1.

 

Key words: Piperaceae, Piper; Peperomia, essential oil composition, antifungal activity, GC-MS.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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