Next to drought, poor soil fertility is the major cause of crops nutrient starvation in Tigray specifically at Mereb lekhe district. Farmers of the study area use different organic and inorganic fertilizers separately and in combination to improve fertility their soils for sorghum production. However, the pace of sorghum production stays constant and/or decreasing with time. Fertilizer efficiency; the type, rate and method of application the local farmers use were the reasons for the steady and/or declining sorghum production. Hence, this study was initiated to determine the yield response of sorghum to microdose fertilizer application. The experiment was set in a randomized complete block design with three replications. The treatments were; farmers’ practice or blanket recommended nitrogen (N) and phosphorous (P) (BRNP) (50kg ha-1 Urea & 100 kg ha-1 DAP), recommended compost (RC) at a rate of 7000 kg ha-1, 75%, 50%, and 25% of BRNP, 75% + 25%, 50% + 50% and 25% + 75% BRNP + RC, respectively all applied with microdosing except the farmers’ practice is in broadcasting method. The highest sorghum grain yield (4201 kg ha-1) and straw yield (19107 kg ha-1) were obtained from recommended compost at a rate of 7000 kg ha-1 and 50% BRNP + 50% RC, respectively. These highest yields might be due to the balanced nutrition and sufficient moisture provided from the microdose applied integrated organic and inorganic fertilizers. In conclusion, combined plant hill placement of organic and inorganic fertilizers contributed to a better sorghum yield than that of the farmers’ practice. Hence, it can be recommended that since the area is less fertile and drought prone integrated use of organic and inorganic fertilizers is crucial. Farmers of the area shall use 7000 kg ha-1 compost and the 75% BRNP second choice for sorghum production.

Keywords: words: Fertilizer, microdosing, grain yield, plant hill, sorghum,