Journal of
Biophysics and Structural Biology

  • Abbreviation: J. Biophys. Struct. Biol.
  • Language: English
  • ISSN: 2141-2200
  • DOI: 10.5897/JBSB
  • Start Year: 2009

JBSB Articles in press

Article in Press

Physical basis of the DNA double helix

Despite the widely spread acceptance that the enthalpy of DNA duplex unfolding does not depend on temperature and is greater for the CG base pair held by three hydrogen bonds than for the AT base pair held by only two hydrogen bonds, direct calorimetric measurements has shown that the enthalpic and entropic contributions of both base pairs are temperature dependent and at all temperatures they are greater for the AT base...

Author(s):Peter Privalov

Article in Press

ANALYTICAL APPROACH TO CANCER THERAPY BY INHIBITION OF BLOCKADE REGULATION IN THE CONTEXT OF PROTEIN VIBRATION

A brief account of discovery of cancer therapy by overcoming the negative immune regulation of cancerous antigens (proteins) with cloned antibodies (proteins) for which Nobel Prize was awarded in Physiology or Medicine in 2018 has been analytically discussed here. These antibodies are now regarded as checkpoint inhibitors. These discoveries have opened a new channel for better treatment of different types of cancer. In...

Author(s):Brajagopal Majumder

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