This study investigates the effect of barley (Hordeum vulgare), black plum (Syzygium cumini) and Chinese tree leaves (Pistacia chinesis) aqueous extracts  on serum glucose, cholesterol, urea, uric acid level and body weight of normal and alloxan-induced diabetic male rabbits. Rabbits were kept in fasting condition for 12 h, then diabetes was induced using alloxan monohydrate (150 mg/Kg) . From the 7th day of diabetes induction, blood serum was collected for glucose analysis. Rabbits having fasting glucose level ≥ 250 mg/dL were considered as diabetic. Rabbits were treated with 1% barley, black plum and Chinese tree aqueous extract to check their effects on the serum glucose, serum cholesterol, serum urea, uric acid and body weight of the animals. Samples were collected after every 72 h for biochemical analysis. It was noted that 1% barley, black plum and Chinese tree aqueous extract reduced 43.92, 39.05 and 32.47% glucose level. Results suggest that oral administration of aqueous extract of barley, black plum and Chinese tree reduced glucose, cholesterol, urea, and uric acid level. Therefore, these medicinal plants should be supplemented as herbal drugs in the treatment of various complex diseases and specially to control diabetes.

 

Key words: Chinese tree leaves, antidiabetic agents, barley, black plum, rabbits, diabetes mellitus.