African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Antimicrobial and cytotoxic activity of Streptomyces sp. from Lonar Lake

Kiran R. Kharat1* Amol Kharat2 and B. P. Hardikar2
  1Department of Biotechnology, Deogiri College, Aurangabad, 431001, India. 2Rofel College of Pharmacy, Vapi, Gujarat, KET’s V.G.Vaze College, Mulund, Mumbai.
Email: [email protected]

  •  Accepted: 23 September 2008
  •  Published: 01 December 2009

Abstract

 

Antibacterial substances from actinomycetes were isolated from marine environment of Lonar Lake and characterized. Out of the 24 isolates subjected to secondary screening, 12 isolates were active against Bacillus subtilis, 13 againstStaphylococcus aureus, 7 against Escherichia coli, 3 against Proteus vulgaris  and 4 against Salmonella typhi. Metabolites in the extract of broth of 48 hrgrownStreptomyces spp. culture no.2 proved to have antimicrobial and cytotoxic against human lung carcinoma cell A549.

 

Key words: C:\Documents and Settings\admin\Desktop\Medical Microbiology and Immunology - Medical Microbiology Journals, Books & Online Media Springer_files\x.gifActinomycetes, antimicrobial activity, cytotoxic activity, human lung carcinoma cells -A549.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

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