African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Antibacterial screening of the root, seed and stembark extracts of Picralima nitida

Nkere, C. K.1* and Iroegbu, C. U.2
  1Federal Medical Centre, Umuahia, Abia State, Nigeria. 2Department of Microbiology, University of Nigeria, Nsukka, Enugu State, Nigeria. ǾCurrent Address: Department of Microbiology, Micheal Okpara University of Agriculture, Umudike Abia State.
Email: [email protected]

  •  Accepted: 09 March 2005
  •  Published: 30 June 2005

Abstract

 

Ethanol, benzene, chloroform and aqueous (cold and hot) extracts of Picralima nitida(seed, stembark and root) were tested against five bacterial strians using the agar-well diffusion method. The ethanol extracts of the root and stembark (Er and Esb) were active against 100% of the test organisms, repectively. The benzene and chloroform extracts exhibited no activity. Of the fifteen extracts teated, 40.0% were active againstStaphylococcus aureus ATCC 12600, 20.0% each against Pseudomonas aeruginosa ATCC 10145 and Escherichia coli ATCC 11775, 33.3% againstBacillus subtilis ATCC 6051 and 13.3% against Salmonella kintambo Human 1,13,23:mt: -. The MIC values for the ethanol extracts range from 6.25 to 50 mg/ml, while the MIC values for the cold water seed extract (CWs) was 50 mg/ml. The results provide a rationalization for the traditional use of P. nitida for the treatment of various diseases.

                          

Key words:  Picralima nitida, ethnomedicine, phytochemical analysis, Nigeria.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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