African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Effects of elevated ambient temperature on embryo implantation in rats

  Huda Yahia Hamid 1,2), Md Zuki Abu Bakar Zakaria 2)*, Nurhusien Yimer 3), Goh Yong Meng 2), Abd. Wahid Haron 4) and Noordin Mohamed Mustapha 5)    
  1Department of Anatomy, Faculty of Veterinary Medicine, University of Khartoum, Sudan. 2Department of Veterinary Preclinical Sciences, Faculty of Veterinary Medicine, University Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia. 3Department of Anatomy, Faculty of Veterinary Medicine, University of Gondar, Ethiopia. 4Department of Veterinary Clinical Studies, Faculty of Veterinary Medicine, University Putra Malaysia, Malaysia. 5Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, University Putra Malaysia, Malaysia.  
Email: [email protected]

  •  Accepted: 23 February 2012
  •  Published: 22 March 2012

Abstract

 

Implantation is a crucial step in mammalian reproduction as it is a gateway to further embryonic development and successful pregnancy. Changes in the environmental factors, such as temperature have adverse effects on reproduction. However, the impact of elevated temperature on the implantation process is not well defined. The objective of this study was to investigate the possible effect of elevated ambient temperature on implantation time and rate. The results revealed that exposure to elevated ambient temperature leads to a delayed implantation and reduced number of implantation sites in Sprague Dawley rats. Moreover, the exposure to elevated temperature resulted in change in the progesterone and estradiol patterns during the implantation time. These findings indicate that elevated temperature disturbs the implantation process.

 

Key words: Elevated temperature, implantation time, number of implantation sites, progesterone and estradiol.