African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Review

BioMatriX: Sequence analysis, structure visualization, phylogenetics and linkage analysis workbench

  Shagufta Kanwal1*, Usman Ali2, Muhammad Irfan Khan1, Zainab noor1, Farhat-ul-ain Mirza1  
  1International Islamic University, H-10, Islamabad, Pakistan. 2Lahore University of Management Sciences, DHA, Lahore Cantt, Pakistan.
Email: [email protected]

  •  Accepted: 14 March 2012
  •  Published: 26 April 2012

Abstract

 

The BioMatriX (Build Mine Xplore) is a bioinformatics work bench (http://www.bmx-biomatrix.blogspot.com) developed for biological science community to augment scientific research regarding genomics, proteomics, phylogenetics and linkage analysis in one platform. BioMatriX offers multi-functional services to perform specific tasks like DNA/RNA/Protein sequence analysis with graphical representations, sequence editing, sequence alignment, restriction enzyme mapping, protein structure visualization, mutation and structure superimposition programs along with phylogenetics tree construction supporting dendrograms, neighbor joining and unweighted pair group method with arithmetic mean (UPGMA) programs. Genomic studies like linkage programs are also implemented. Special emphasis has been paid to integrate all the resources in one software so that the researcher does not have to install numerous pieces of software to analyze his data.

 

Key words: Bioinformatics, linkage, visualizer, alignment, superimposition, phylogenetics.