African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

The micro-minerals composition in serum of rabbits (Oryctolagus cuniculus) infected with Trypanosoma congolense

  S. A. Ameen1*, E. A. Okewole2, O. S.Adedeji1, K. A. Ogundipe2 and A.  A. Okanlawon2  
  1Department of Animal Production and Health, LAUTECH, Ogbomoso, Oyo State, Nigeria. 2Faculty of Veterinary Medicine, University of Ibadan, Ibadan, Nigeria.
Email: [email protected]

  •  Accepted: 09 March 2011
  •  Published: 03 January 2012

Abstract

 

Sixteen (16) rabbits aged between 6 to 12 months were infected with fresh stock ofTrypanosoma congolense (Gboko strain) intravenously at the rate of 1.0 × 106/ml. Animals were classified into two groups; groups A were infected, while group B served as uninfected controls. Samples from the infected and the uninfected controls showed a  significant increase in the levels of sodium (Na+), calcium (Ca2+), phosphate (PO42-) and blood urea nitrogen (BUN) (P < 0.05) and a significant decline in the levels of potassium (K+) and bicarbonate (HCO32-) (P < 0.05). Therefore, the alterations in the compositions of these micro-minerals in the serum of rabbits may suggest that, they could have a role in the pathogenesis of trypanosomosis due to T. congolense infection.

 

Key words: Rabbits, micro-minerals, Trypanosoma congolense,   pathogenesis.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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