African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Review

The biochemical, physiological and therapeutic roles of ascorbic acid

Oluwafemi O. Oguntibeju
Oxidative Stress Research Unit, Department of Biomedical Sciences, Faculty of Health and Wellness Sciences, Cape Peninsula University of Technology, Bellville, South Africa. 
Email: [email protected], [email protected]

  •  Accepted: 21 November 2008
  •  Published: 29 December 2008

Abstract

 

Ascorbic acid is an important micronutrient necessary for a significant number of metabolic reactions in humans and other primates. It is a strong reducing agent involved in reduction reaction and it is structurally related to glucose. Experimental and epidemiological studies have documented the biochemical, physiological and therapeutic roles of ascorbic acid. It is an essential water-soluble antioxidant vitamin derived from exogenous source; thus its role in human health is worthy to be considered particularly because of the current global economic trend. The biochemical, physiological and therapeutic roles of ascorbic acid is reviewed, providing further insights into the role of ascorbic acid in biological functions.

 

Key words: Ascorbic acid, human health, disease, biological function, therapeutic roles.