Abstract

In this study, the antioxidant activity and phytochemical analysis of extracts from the bark of Fagara zanthoxyloides and seeds of Mucuna pruriens were performed. Phytochemical analysis quantified total polyphenols, flavonoids, tannins and anthocyanins and the antioxidant activity was evaluated by DPPH method. The high levels of polyphenols are obtained from the aqueous extract of F. zanthoxyloïdes (488.6 ± 1.1 GAE/g) and the methanolic extract of Mucuna pruriens (142.9±12.9 GAE/g). The acetone extracts of F. zanthoxyloïdes and ethyl acetate extract of M. pruriens showed better flavonoid levels with 9.80±0.72 and 15.6±0.02 QE/g, respectively. For tannins, the aqueous extracts of F. zanthoxyloides and methanolic from M. pruriens showed a level of 19.2±1.41 and 5.7±0.74 CE/g. The antioxidant activity of the different extracts of the plants proved the highest antioxidant activity for the acetone extract of F. zanthoxyloïdes (IC₅₀=3.44 mg/L). The methanolic extract of M. pruriens showed weak antioxidant activity IC₅₀=3176.22 mg/L, the highest antioxidant activity of F. zanthoxyloïdes.

Key words: Mucuna pruriens, Fagara zanthoxyloïdes, polyphenols, antioxidant, in vitro activity, DPPH.