African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Short Communication

Studies on the expectorant, antitussive and antiasthmatic properties of asterosaponin extracted from Luidia quinaria

Chenghua Guo1,2*, Xuexi Tang1, Xinwei Dong2 and Yan Yang1
  1College of Marine Life Sciences, Ocean University of China, Qingdao 266003, China. 2Scientific and Technological College of Chemistry and Biology, Yantai University, Yantai 264005, China
Email: [email protected]

  •  Accepted: 30 April 2009
  •  Published: 01 December 2009

Abstract

 

The aim of this study was to analyze the expectorant, antitussive and antiasthmatic effects of asterosa-ponin from Luidia quinaria through secretion of phenol red from mouse tracheas, frequency of cough caused by ammonia in mice and asthma induced by histamine in guinea pig, respectively. Results showed that asterosaponin extracted from L. quinaria at doses of 20 mg/kg and 40 mg/kg could signi-ficantly increase secretion of phenol red from mouse tracheas, prolonged the latent period of asthma induced by histamine, and decreased the frequency of cough caused by ammonia. In conclusion, asterosaponin from L. quinaria has obvious antitussive, antiasthmatic and expectorant effects.

 

Key words: Luidia quinaria, asterosaponin, antitussive, antiasthmatic, expectorant.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

Back to Vol. 8 No. 23
Back to articles
  • Articles on Google by:
SUBSCRIBE TO RSS
SUBMIT MANUSCRIPT
CONFERENCES