African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12488

Full Length Research Paper

Antimicrobial activity of silver nanoparticles synthesized by the fungus Curvularia inaequalis

Helinando P. de Oliveira1,2*, Leonardo S. Cavalcanti1, Noelly B. Cavalcanti1, Ismara de S. Nascimento1, Sergio F. Pascholati3, Luis F. P. Gusmão4, Alan Greison C. Macêdo1 and Mateus Matiuzzi da Costa1
1Instituto de Pesquisa em Substâncias Bioativas, Universidade Federal do Vale do São Francisco, 48920-310, Juazeiro, BA, Brazil. 2Instituto de Pesquisa em Ciência dos Materiais, Universidade Federal do Vale do São Francisco, 48920-310, Juazeiro, BA, Brazil. 3Escola Superior de Agricultura Luiz de Queiroz – USP, 13418-900, Piracicaba, SP, Brazil. 4Universidade Estadual de Feira de Santana, 44031-460, Feira de Santana, BA, Brazil.  
Email: [email protected]

  •  Published: 15 May 2013

Abstract

Silver nanoparticles have been widely reported in literature due to their vast industrial application in different areas. In this work, we explored a simple procedure for the biosynthesis of silver nanoparticles at room temperature from the action of Curvularia inaequalis as reduction agent. The degree of aggregation and size of biosynthesized particles were optimized from a factorial design involving combined variation of three different parameters of preparation. The resulting colloidal dispersion of silver nanoparticles presented strong antimicrobial activity against Escherichia coli andKlebsiella pneumoniae in an indication that C. inaequalis represents a new potential candidate for alternative biosynthesis of silver nanoparticles with antimicrobial activity.

 

Keywords: Antimicrobial activity, fungi, silver nanoparticles.