African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Identification and antifungal activity of Streptomyces sp. S72 isolated from Lake Oubeira sediments in North-East of Algeria

  Adel Ayari*, Houda Morakchi and Kirane Gacemi Djamila  
  Department of Biochemistry, Badji Mokhtar University, B.O 12, 23000 Annaba, Algeria.
Email: [email protected]

  •  Accepted: 28 December 2011
  •  Published: 05 January 2012

Abstract

 

The aim of this study was to identify a new actinomycete isolate Streptomyces sp. S72 with antifungal activity from sediments of Oubeira’s Lake located at the North-East of Algeria. This isolate was identified based on a great variety of morphological, cultural, physiological and molecular characteristics analysis of 16S rDNA sequence. The test of antifungal activity for several pathogens fungi causing invasive aspergillosis and systemic candidiasis revealed that the Streptomyces sp. S72 was a good moderate antifungal compound producer against Aspergillus fumigatus andCandida albicans, and had no activity against Aspergillus flavus, Aspergillus niger,Candida pseudotropicalis and Candida tropicalis.

 

Key words: Streptomyces, Oubeira’s Lake, antifungal activity, Candida albicans,Aspergillus fumigatus.