Short Communication
Abstract
IC50 for nine cancer cell lines was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assays. In KM mice bearing sarcoma S180 that was treated with subcutaneous (s.c.) injection of antibiotic BS, marked cures were obtained. In terms of tumor weight, the treated/control = 0.43. The conclusion is that BS merit further investigation as a potential anti-cancer candidate drug.
Key word: Antibiotic, Bacillus subtilis, in vivo, in vitro, antitumor.
Abbreviation
MTT, 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; s.c, subcutaneous.
Copyright © 2024 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0