African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Derivation of a formula for adjusting the total serum calcium in Nigeria environment

O. F. Ogunkolo1*, A. A.  Amballi2, F. A. Adenaike2, Olukoya Taiwo2
1Department of Physiology, Obafemi Awolowo College of Health Sciences.  Olabisi Onabanjo University Teaching Hospital, Shagamu Nigeria. 2Department of Chemical Pathology Obafemi Awolowo College of Health Sciences.  Olabisi Onabanjo University Teaching Hospital, Shagamu Nigeria.
Email: [email protected]

  •  Accepted: 27 May 2006
  •  Published: 16 June 2006

Abstract

 

The total calcium concentration, total protein, albumin and globulin were estimated for 302 patients that reported for serum calcium estimation at the clinical biochemistry laboratory of the Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria. Based on regression analysis, three formulae were derived for adjusting the total serum calcium concentration. It was observed that the total serum concentration correlated closely with albumin (a = 0.919 70) but poorly correlated with total protein (a = -0.25 960); where a = correlation coefficient. Adjusted calcium = total calcium – (0.91972 x albumin) + 3.70429 was obtained.

 

Key words: Total serum calcium, adjusting formula, serum albumin.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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