African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Aqueous ethanolic extract of Cochlospermum planchonii rhizome enhances spermatogenesis in male albino rats

A. H. Abu1*, D. O. Ochalefu2 and A. Ibrahim3        
1Department of Veterinary Physiology, Pharmacology and Biochemistry, College of Veterinary Medicine, University of Agriculture, P. M. B. 2373, Makurdi, Nigeria. 2Department of Biochemistry, College of Health Sciences, Benue State University, Makurdi, Nigeria. 3Department of Medicine, Faculty of Veterinary Medicine, University of Maiduguri, Maiduguri, Nigeria.
Email: [email protected]

  •  Accepted: 15 June 2012
  •  Published: 31 July 2012

Abstract

Cochlospermum planchonii has numerous therapeutic benefits and is widely used in folklore medicine of many African countries. This study was designed to investigate the effects of aqueous ethanolic extract of Cochlospermum planchonii root on sperm characteristics of albino rats. Animals were assigned into four groups comprising a control, which received only distilled water and treatment groups at the doses of 100, 200 and 400 mg/kg body weight daily for 30 days, respectively. The aqueous ethanolic extract of Cplanchonii did significantly increase (P<0.05) the weights of the testes and accessory sex organs. Sperm count and sperm motility of rats given the extract increased (P<0.05) relative to the control. Percentages of abnormal sperm cells remained unchanged. The results of this study indicate that aqueous ethanolic extract of Cochlospermum planchonii increased spermatogenesis in the male rats.

 

Key wordsCochlospermum planchonii, sperm characteristics, reproduction, Wistar rats.