African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12486

Full Length Research Paper

Effect of Cassia hirsuta (L) extract on DNA profile of some microorganisms

M. K. Oladunmoye, F. C. Adetuyi and F. A. Akinyosoye
Department of Microbiology, Federal University of Technology, Akure, Nigeria.
Email: [email protected]

  •  Accepted: 11 August 2006
  •  Published: 04 February 2009

Abstract

 

The effect of ethanol extract of leaf of Cassia hirsute (L) on the DNA profile of some selected pathogenic microorganisms were investigated using PCR-RAPD analysis to generate DNA fingerprint. The change in molecular configuration of organisms with and without extract shows a wide disparity between the sensitive and the resistant organism. Thus, this study demonstrates that some of the organisms are susceptible to the antimicrobial activity of C. hirsute extract while others are resistant.

 

Key words: Cassia hirsuta, DNA finger printing, antimicrobial activity.