The n-butanol purified saponin extract of sorghum bicolor were screened for anti-bacterial activity against three pathogenic microbes; Escherichia coli,Staphylococcus aureus and Candida albicans. The extract inhibited the growth of the S. aureus. It was concluded that the saponins have inhibitory effect on gram-positive organism but not on gram negative organism and the fungi.
Key words: Sorghum bicolor, saponins, antimicrobial activity.
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