African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12209

Full Length Research Paper

Evaluation of the antimicrobial activity of saponins extract of Sorghum Bicolor L. Moench

Soetan k. O.1*, Oyekunle M. A.2, Aiyelaagbe O. O.3 and Fafunso M. A.4
1Department of Veterinary Physiology, Biochemistry and Pharmacology, University of Ibadan, Ibadan, 2Department of Veterinary Microbiology and Parasitology, University of Agriculture, Abeokuta. 3Department of Chemistry, University of Ibadan, Ibadan. 4Department of Biochemistry, University of Ibadan, Ibadan.
Email: [email protected]

  •  Accepted: 27 June 2006
  •  Published: 04 December 2006

Abstract

The n-butanol purified saponin extract of sorghum bicolor were screened for anti-bacterial activity against three pathogenic microbes; Escherichia coli,Staphylococcus aureus and Candida albicans. The extract inhibited the growth of the S. aureus. It was concluded that the saponins have inhibitory effect on gram-positive organism but not on gram negative organism and the fungi.

 

Key wordsSorghum bicolor, saponins, antimicrobial activity.