African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Review

In silico approach towards H5N1 virus protein and transcriptomics-based medication

Usman Sumo Friend Tambunan* and Arli Aditya Parikesit
Department of Chemistry, Faculty of Mathematics and Science, University ofIndonesia Depok 16424, Indonesia.  
Email: [email protected].

  •  Accepted: 31 December 2012
  •  Published: 22 May 2013

Abstract

H5N1 influenza A virus is a serious threat to human population. With a considerablemortality rate, strategies for coping with the infection are being developed. Ourresearch group and some others investigated the potentialtherapeutic and preventivemeasures for tackling H5N1 infections. Protein-based and transcriptomics analysesare getting more important in this field. The trends towards the integration of bothprotein-based and transcriptomics for H5N1 analysis are indeed feasible.

 

Key words: H5N1, protein-based, transcriptomics, siRNA, hemagglutinin (HA), matrix1 (M1), non-structural 1 (NS1), neuraminidase (NA), and matrix2 (M2).