Abstract

The genetic diversity of the complete coding sequence (CDS) of Foxl2 gene from 19 species, including Mus musculus, Rattus norvegicus, Homo sapiens, Pan troglodytes, Sus scrofa, Gallus gallus, Bos taurus, Oryctolagus cuniculus, Oryzias luzonensis, Oryzias latipes, Xenopus laevis, Oreochromis aureus, Danio rerio, Trachemys scripta, Ellobius lutescens, Alligcltor mississippiensis, Kryptolebias marmoratus, Odontesthes hatchery and Odontesthes bonariensis, was analyzed using bioinformatics. The characteristics of composition of nucleic acid and amino acid, leader peptides, signal peptide, trans-membrane topological structure, hydrophobicity or hydrophilicity, protein secondary structure and structure domain were also analyzed. The results showed that a total of 447 polymorphic sites were detected from 33 sequences of 19 species, from which 24 hapolotypes were sorted. The genetic diversity of the Foxl2 gene CDS was rich within and among species. The Foxl2 protein in these species was a non trans-membrane protein without leader peptides and has signal peptide in N-terminal, with the hydrophilic polypeptide chain. The main motifs of predicted secondary structure of Foxl2 are random coil and alpha helix. There is a common conserved structure domain.

Key words: Foxl2 gene, bioinformatics, genetic diversity, genetic differentiation.