African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Effects of polysaccharide from Lycium barbarum in alloxan-induced diabetic mice

Zhengwei Zhou1, Longjun Jing2*, Guowen Cui3, Qiang Feng2 and Yuanshi Xiao2
  1Hunan City University, Yiyang, Hunan Province, 413000, P. R. China. 2Qujing Normal University, Qujing, Yunnan Province, 655011, P. R. China. 3Yuxi Normal University, Yuxi, Yunnan Province, 653100, P. R. China.
Email: [email protected], [email protected]

  •  Accepted: 14 October 2009
  •  Published: 01 December 2009

Abstract

 

A study was undertaken to evaluate the effects of polysaccharide from Lycium barbarum (LBP) in alloxan-induced diabetic mice. The various parameters studied included body weight, fasting blood glucose levels, total cholesterol (TC) andtriglyceride (TG) in diabetic and normal mice. LBP treatment (20, 40 mg/ kg body weight) for 28 days resulted in a significant decrease in the concentration of fasting blood glucose (FBG), total cholesterol (TC) and triglyceride (TG) in diabetes mellitus mice. Furthermore, LBP significantly increased body weight (bw). The data demonstrated LBP at the dose of 40 mg/kg bw exhibited the optimal effect.

 

Key words: Polysaccharide from Lycium barbarum, effect, diabetic.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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