African Journal of

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12487

Full Length Research Paper

Acute toxicity assessment of crude lead-extract from electronic waste materials in Nigeria

O. C. Eneh1* and P. A. Akah2
  1Institute for Development Studies, Enugu Campus, University of Nigeria, Nsukka, Nigeria. 2Department of Pharmacoloy and Toxicology, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria.
Email: [email protected]

  •  Accepted: 05 October 2012
  •  Published: 01 November 2012



Lead, with its toxic emission and pollution, is one of the hazardous chemical components of electronic wastes (e-wastes) rapidly generated in developing countries. This study assessed the environmental health effects of crude lead extracted from e-wastes materials, as determined by its acute toxicity (rat, oral). Diluted HNO3 and hot concentrated HCl tests were used to confirm the presence of lead in the extract. LD50 (400 mg/kg) showed higher toxicity than the lowest toxic dose of 790 mg/kg reported in literature. There was a perfect positive correlation between the log dose and dead percentage, which was significant at 0.014, with 0.99° of confidence. The R2 (0.839) and significance F (0.029) showed high reliability. In view of this, we recommend the inclusion of enlightenment and making/enforcing adequate policies for improved management and control of e-waste materials.

Key words: Environmental health effect, toxic chemical component, e-waste


IN, Irregular nuclei; DNS, denaturation of myelin; NMDA, N-methyl-D-aspartate; PNS, peripheral nervous system; CNS, central nervous system.